Medicinal Chemistry

Medicinal Chemistry structures

Medicinal Chemistry at the U of M

Department of Medicinal Chemistry Faculty work with diverse graduate students, post-doctoral fellows and researchers at the interface of Chemistry and Biology.  Learn more

Medicinal Chemistry

Students on CampusMedicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.

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Research Areas

Medicinal Chemistry professor and student

Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.

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Student Spotlight: Connor McDermott

Connor McDermottACS Chemical Computing Group Research Excellence Award in Medicinal Chemistry

This competitive national award recognizes outstanding graduate students focusing on computing in medicinal chemistry, whose research is of high quality and significance. Connor will also be honored during a ceremony at the ACS COMP Division Poster Session Spring 2018 New Orleans ACS National Meeting.

Faculty Spotlight: Natalia Tretyakova

Tretyakova Research GroupNatalia Tretyakova has been awarded a $1.7 million grant from the National Institutes of Health for the project "Smoking-Induced Epigenetic Changes in the Lung: Role of DNA Demethylation," on which she is the principal investigator.

Dr. Carrie Haskell-Luevano has been elected to serve on the Institute for Translational Neuroscience Steering Committee, which brings together neuroscience leaders from different departments and centers at the University of Minnesota. The Steering Committee is tasked with utilizing breakthrough neuro-related research to develop processes for improving clinical care and new treatments and therapies across the health sciences at the University.

Drs. Gunda Georg and Shameem Syeda have been featured on the front page of the Star Tribune's Science and Health section discussing the process of researching and developing a male birth control pill. While the article highlights the recent promising results from testing ouabain - a plant extract that has long been used by African hunters to create poison-tipped arrows - it also notes that, "Ouabain is just one of a handful of male contraceptive projects that Georg and Syeda are working on simultaneously.

Congratulations to Dr. Natalia Tretyakova, who has been selected as a 2018 Distinguished McKnight University Professor! The McKnight professorship honors and rewards the University of Minnesota's most distinguished and highest-achieving mid-career faculty who have recently attained full professor status — particularily those who have made significant advances in their careers at the University of Minnesota, whose work and reputation are identified with the University, and whose accomplishments have brought great renown and prestige to Minnesota. Dr.

Congratulations to Joseph Buonomo of the Aldrich lab, who has been selected to receive the 2018 Abul-Hajj/Hanna Exceptional Graduate Student Award in Medicinal Chemistry! This award is given each year based on a graduate students' quantity and quality of research accomplishments, the quality of the original research proposal for the oral exam, the quality of seminars and colloquia, the Graduate Course grade-point average since entering the program, and service and citizenship in departmental affairs.



Researcher at Biomedical Discovery District
Research Facilities

Make use of the Department's over 30,000 square feet of modern research laboratory space located within the Academic Health Center and the Biomedical Discovery District.

Research in ITDDInstitute for Therapeutics Discovery & Development

The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.

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