Medicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.
Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.
Will blue packets replace pink ones soon?
A paper authored by Drs. Gunda Georg, Jon Hawkinson, Kwon Ho Hong, and Shameem Sultana Syeda, all from the Institute for Therapeutics Discovery and Development, was publicized in the most recent press release of the American Chemical Society. The paper explores the potential of the plant extract ouabain as a male contraceptive agent. Ouabain has long been used by African hunters as the lethal agent for poison-tipped arrows, but in small doses it has also shown efficacy in lowering fertility rates in males.
Dr. Gunda Georg has been featured in multiple media outlets for her work into the development of a male birth control pill. The articles highlight the recent exploration into the efficacy of ouabain, a plant extract that has long been used by African hunters to create poison-tipped arrows. A form of ouabain is also produced in small amounts in the human body and studies have shown that men with higher levels of ouabain have lower fertility, making it a promising candidate as a male contraceptive agent. You can read more about ouabain and Dr.
Dr. Rory Remmel has won the James R.
Student Spotlight: Connor McDermott
ACS Chemical Computing Group Research Excellence Award in Medicinal Chemistry
Faculty Spotlight: Natalia Tretyakova
Natalia Tretyakova has been awarded a $1.7 million grant from the National Institutes of Health for the project "Smoking-Induced Epigenetic Changes in the Lung: Role of DNA Demethylation," on which she is the principal investigator.
The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.