SUMMER 2018
JUNE 5
Potentiation of Multiple Antibacterial Agents in MRSA and M. tuberculosis
John Schultz, Aldrich Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
June 7
Sperm Tales: The Manchette as a Target for Male Contraception?
Dr. Jerry Strauss, Professor, Virginia Commonwealth University School of Medicine
105 717 Delaware Street SE (Twin Cities), 12:30pm
June 8
The Synthesis and Characterization of Novel Melanocortin-4 Receptor Probes
Dr. Mark Ericson, Haskell-Luevano Lab
105 717 Delaware Street SE (Twin Cities), 3:30-5:00pm
JUNE 26
N-Terminal BET Bromodomain Inhibition using MAP-Kinase Inhibitors
Anand Divakaran, Pomerantz Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
JULY 24
Structural Targeting of the Hyaluronan Binding Domain of CD44
Bill McCue, Finzel Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
JULY 31
Mining Unexpected Chemical Space: Bioterror Countermeasures and Geopharmaceuticals
Connor McDermott, Ambrose Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
AUGUST 7
Development of Fibronectin-based Chemically Self-assembled Nanorings (CSANS) for Immunotherapy
Ellie Mews, Wagner Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
AUGUST 14
Development of Protein and DNA Adduct Biomarkers from Carcinogens in Cooked Meats and Tobacco Smoke by Liquid Chromatography-Mass Spectrometry
Dmitri Konorev, Turesky Lab
1-450 Moos Tower (Twin Cities), 3:30-5:00pm
AUGUST 28
Synthesis and Evaulation of Novel β-lactam Antibiotics for Drug-resistant Tuberculosis
Malcolm Cole, Aldrich Lab
105 717 Delaware Street SE (Twin Cities), 3:30-5:00pm
FALL 2018
SEPTEMBER 4
New Mechanisms for Excision Repair of Interstrand DNA Crosslinks
Brandt Eichman, Ph.D., Professor, Dept. Biological Sciences & Biochemistry, Vanderbilt University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
SEPTEMBER 11
Development of Selective M5 Negative Allosteric Modulators for Opioid Use Disorder
Carrie Jones, Ph.D., Assistant Professor, Dept. Pharmacology, Vanderbilt University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
SEPTEMBER 18
Restoring Vision through Chemical Photoswitches; A Potential Therapy for Retinitis Pigmentosa
Alexander Hurben, Doran Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
SEPTEMBER 25
The Development and Usage of Fluorescent Probes for Surgical Tumor Removal
Samantha Kennelly, Harki Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
OCTOBER 2
Design, Synthesis, and Evaluation of New Drugs for African Sleeping Sickness
Amy Dounay, Ph.D., Assistant Professor, Dept. Chemistry & Biochemistry, Colorado College
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
OCTOBER 9
Design of Novel PDE2A Inhibitors for the Treatment of Cognitive Disorders
Brian Gabet, Georg Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
OCTOBER 16
**Portoghese Lectureship**
Allosteric Modulators of GPCRs as a Novel Approach for Treatment of Schizophrenias
P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology and Director of Center for Neuroscience Drug Discovery, Vanderbilt Brain Institute, Vanderbilt University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
OCTOBER 23
**Taito "Ty" Soine Memorial Lecture**
Discovery of Novel Anticoagulants: New Frontiers and Lessons Learned
Ruth Wexler, Ph.D., Executive Director, Bristol-Myers Squibb
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
OCTOBER 30
Phenazine Antibiotics and Indole Alkaloids: New Platforms for Discovery
Robert W. Huigens III, Ph.D., Assistant Professor, Dept. Medicinal Chemsitry, University of Florida
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
NOVEMBER 6
A Molecular Chaperone Approach to Treat Transthyretin Amyloidosis
Jacob Bouchard, Doran Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
NOVEMBER 13
Targeting the Immunomodulator SPPL2a as a Novel Approach to Treating Multiple Sclerosis
Jacob Patterson, Doran Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
NOVEMBER 20
IRAK-4 Inhibitors for Inflammation
Md Abdullah Al Noman, Georg Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
NOVEMBER 27
Title: TBD
Jennifer Allen, Ph.D., Director of Medicinal Chemistry, Amgen
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
DECEMBER 4
Inhibitors of Post-translational Proteases: Overcoming Resistance to Targeted Therapies in Cancer
James Janetka, Ph.D., Associate Professor, Dept. Biochemistry & Molecular Biophysics, Washington University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
DECEMBER 11
**Distinguished Lectureship**
How Cytochrome P450 and Other Redox Enzymes Make and Break C-C Bonds: Relevance to Drugs and Natural Products
F. Peter Guengerich, Ph.D., Tadishi Inagami Professor, Dept. Biochemistry, Vanderbilt University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
SPRING 2019
JANUARY 22
Title: TBD
Donna Huryn, Ph.D., Research Professor, Dept. Pharmaceutical Sciences, University of Pittsburgh
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
JANUARY 29
Targeting and Probing RNA: Biochemical and Biophysical Approaches
Christine Chow, Ph.D., Professor, Dept. Biochemistry, Wayne State University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
FEBRUARY 5
MeCP2 Gene Therapy: A Promising New Treatment for Rett Syndrome
Caitlin Jokipii Krueger, Tretyakova Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
FEBRUARY 12
Targeting the Stroma-tumor Interaction in Pancreatic Cancer
Erik Faber, Georg Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
FEBRUARY 19
TBD
FEBRUARY 26
Discovery and Identification of Allosteric Inhibition of SHP2: Development of a Potent, Selective and Orally Efficacious Inhibitor
Nan Wang, Georg Lab
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
MARCH 5
Biophysical Chemistry of Large Antiviral-Polyamide DNA Interactions
Cynthia Dupureur, Ph.D., Professor & Chair, Dept. Chemistry & Biochemistry, University of Missouri St. Louis
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
MARCH 12
Deptartmental Safety Training
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
MARCH 26
2019 MIKI PRACTICE TALKS
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
APRIL 9
**Distinguished Lectureship**
The Dopamine Synapse
David Sulzer, Ph.D., Professor, Dept. Neurology, Columbia University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
APRIL 16
**Distinguished Lectureship**
Title: TBD
Wendy Young, Ph.D., Senior Vice President, Small Molecule Drug Discovery, Genentech, Inc.
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
APRIL 23
Human Milk Oligosaccharides as Narrow-Spectrum Antimicrobial Agents Against Group B Strep
Steven Townsend, Ph.D., Assistant Professor, Dept. Chemistry, Vanderbilt University
1-451 Moos Tower (Twin Cities), 3:30-5:00pm
