2024
2023
Fan Wang, PhD
Thesis: Approaches to Understanding Antiretroviral Pharmacology in Difficult-to-access Tissues for HIV Treatment and Prevention
Employer: AbbVie
Rui Zhong, PhD
Thesis: Cerebral Vasculature as a Therapeutic Target to Combat Alzheimer’s Disease
Employment: Post-Doc Research Associate at University of North Carolina at Chapel Hill
2022
Mutaz Jaber, PhD
Thesis: Evaluation of Pharmacostatistical Model Components Using a Nonlinear Mixed-effect Approach
Employer: Gilead Sciences
Siddhee Sahasrabudhe, PhD
Thesis: Application of Clinical Pharmacology in Rare Diseases and Non-suicidal Self-injury
Employer: Pfizer
Abdelrahman Saqr, MS
Thesis: Precision Medicine Approaches to Immunosuppression Using Pharmacogenomics and the Microbiome
Takuto Takahashi, PhD
Thesis: Individualized Drug Use in Hematopoietic Cell Transplantation: Application of Pharmacometric and Pharmacogenomic Study
Employer: Boston Children's Hospital/Dana-Farber Cancer Institute
Ya-Feng (Jay) Wen, PhD
Thesis: Toward Individualized Medicine in Understudied Populations using Personal Genome and Microbiome
Employer: Gilead Sciences
2021
Shen Cheng, PhD
Thesis: Understanding the Impact of Pharmacogenetic Differences in Drug-Drug Interactions (DDIs): A Model-Based Approach to Predict Differences in Drug Exposure
Employer: Metrum Research Group
Angela Jeong, PhD
Thesis: Protein prenylation in the pathogenesis of Alzheimer’s Disease and its therapeutic potential
Employer: Postdoctoral Fellowship at University of North Carolina, Chapel Hill
Sarah Kim, PhD
Thesis: Improving Delivery of Therapeutics to Targeted Tissues in Lysosomal Diseases
David Margraf, PhD
Thesis: Quantitative Methods for Evidence Building in Clinical Pharmacology and Pharmaceutical Outcomes Research
Employer: Center for Infectious Disease Research and Policy, University of Minnesota
Joshua Mentzer, MS
Project: Using Machine Learning in High Throughput Drug Screening of In-Vitro Drug Response Data to predict In-Vivo Clinical Response for Metastatic Castration-Resistant Prostate Cancer
Student: Professional pharmacy program
2020
Ashwin Karanam, PhD
Thesis: Quantitative Pharmacological Approaches for Characterizing Lamotrigine Pharmacokinetics in Special Populations of Pregnancy, Postpartum and Breastfeeding Infants to Prospectively Optimize Dosing
Employer: Pfizer
Scott Luisi, MS
Thesis: Topiramate Induced Alteration in Frontal Lobe eLORETA-ICA Resting State Network Activity is Associated with Baseline Semantic Fluency Performance
Abhishek Sathe, PhD
Thesis: Clinical Pharmacology of First- and Second-Line Treatments of Convulsive Status Epilepticus
Employer: Gilead Sciences
2019
Samuel Callisto, PhD
Thesis: Linking Topiramate Exposure to Changes in Electrophysiological Activity and Behavioral Deficits through Quantitative Pharmacological Modeling.
Employer: Metrum Research Group
Natalie Schmitz, PhD
Thesis: Orphan Drug Development: The Regulatory, Economic, and Scientific Aspects of Intravenous Baclofen
Employer: Assistant Professor, College of Pharmacy, University of Wisconsin-Madison
Irene Vuu, PhD
Thesis: Development of Parenteral Drugs for the Treatment of Seizure Emergencies
Employer: Scientist, Clinical Pharmacology, Amgen
2018
Abeer Alharbi, MS
Thesis: Phase 1 Clinical Trials of Anticancer Agents
Student at Oxford University, England
Vaishnavi Soundararajan, MS
Thesis: Characterization of Simulated Lamotrigine Clearance during Pregnancy using Regression Analysis
2017
Ali Alhadab, PhD
Thesis: The Utility of Pharmacometrics in Drug Development and Pharmacotherapy of Antimicrobials
Employer: Pfizer
David Hottman, PhD
Thesis: The Role of High-Density Lipoproteins and Related Pathways in Alzheimer’s Disease
Employer: University of Minnesota
Taraswi Mitra Gosh, PhD
Thesis: Pharmacogenomics of Chemotherapeutic Agents: Carboplatin and Paclitaxel
Employer: University of Minnesota
Cristina Peterson, PhD
Thesis: Alleviation of Chronic Neuropathic Pain by Agmatine Requires the GluN2B Subunit of the NMDA Receptor
Employer: University of Minnesota
Youssef Roman, PhD
Thesis: Pharmacogenetic Investigations Using Community-Based Participatory Research to Address Health Disparities in Minnesota Hmong
Employer: United States Food and Drug Administration (FDA)
2016
Mariam Ahmed, PhD
Thesis: Application of Pharmacometrics to Rare Diseases
Employer: United States Food and Drug Administration
Chay Lim, PhD
Thesis: Application of Quantitative Pharmacological Modeling to Improve Drug Therapy in Older Adults
Employer: Pfizer
Kinjal Sanghavi, PhD
Thesis: Personalizing Therapy in Transplantation: Focus on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Drugs Used in Hematopoeitic Stem Cell and Kidney Transplant
Employer: Bristol-Myers Squibb
2015
Neha Bhise, PhD
Thesis: MicroRNAs As Predictors of Nucleoside Analog Sensitivity in Acute Myeloid Leukemia
Caroline Churchill, PhD
Thesis: The Impace of Gene Transfer of Arginine Decarboxylase to the Central Nervous System on Opioid Analgesic Tolerance
Employer: University of Minnesota
Aaron Gillman, PhD
Thesis: Vaccination and Host-Targeted Interventions for Staphylococcus aureus Exotoxin-Mediated Diseases.
Employer: Arctic University of Norway
Malek Okour, PhD
Thesis: The Pharmacokinetics of Enterohepatic Circulation
Employer: GlaxoSmithKline
Alumni Spotlight: Fall 2018 ECP Gazette
Krista Johnson, PhD
Thesis: Characterization of the Relationship Between Whole Blood and Plasma Topiramate Concentrations
Employer: Clinical Scientist, Abbott Laboratories
Harrison Tam, PhD
Thesis: The Effect of Obesity and High-Fat Diet on Cardiovascular Risk and Intestinal Drug Metabolism
Employer: University of Kentucky
2014
Mary Holmay, PhD
Thesis:N- acrtylcysteine: pharmacokinetics and effects in selected neuro degenerative disorders
Employer: Director, Medical Affairs, Greenwich Biosciences
Suresh Agarwal, PhD
Thesis: Clinical Pharmacology and Pharmacometric Analyses of CNS Drugs Used in the Acute Management of Seizures and Spasticity
Employer: Principal Scientist, Amgen
Jie Zhou, PhD
Thesis: Mitigating Oxidative Stress in Childhood Cerebral Adrenoleukodystrophy – An Investigation of N-acetylcysteine Pharmacology
Employer: Director, Pharmacometrics, Nuventra Pharma Sciences
2013
Jia Kang, MS, PhD
Thesis: Pharmacometric Analyses of drug exposure and response data
Employer: Research Scientist, Pharmacometrics at Metrum Research Group LLC
Manoj Chiney, PhD
Thesis: Effect of obesity on hepatic drug metabolism
Employer: Research Investigator, Bristol-Myers Squibb
Gavin Bart, PhD
Thesis: Methadone Population Pharmacokinetics: Toward understanding the dose-response relationship in the treatment of opiate addition
Employer: Division Director of Addictive Medicine, Hennepin County Medical Center, Minneapolis, MN
2012
Chaitali Passey, PhD
Thesis: Application of pharmacometrics for covariate selection and dose optimization of tacrolimus in adult kidney transplant recipients
Employer: Research Investigator, Bristol Myer Squibb, Oncology/Immunology Division, New Jersey
Ghada F. Ahmed, PhD
Thesis: Pharmacometric Analyses of Anti-epileptic Drugs in Elderly Patients: Applications to Carbamazepine, Gabapentin and Topiramate
Employer: Senior Clinical Pharmacokineticist, Abbott Laboratories, No. Chicago, IL
Akshanth Polepally, PhD
Thesis: Pharmacometric Analyses of Lamotrigine in Special Populations: Application to Pregnant Women, Younger Adult and Elderly Epilepsy Patients
Employer: Senior Clinical Pharmacokineticist, AbbVie Inc., Chicago, IL
Azher Arafah, PhD
Thesis: Studies investigating the impact of select genotypes on the pharmacological effect of fenofibrate
Employer: Assistant Professor, Clinical Pharmacy Department, College of Pharmacy King Saud University, Saudi Arabia
Heather Vezina, PhD
Thesis: Application of Pharmacometric Methods to Studies of Antiviral Prophylaxis After Solid Organ Transplantation
Employer: Research Investigator, Bristol-Myers Squibb
Alumni Spotlight: Spring 2018 ECP Gazette
Pornpimol Kijsanayotin PhD
Thesis: Association of Genetic Variants in CYP ARCB1 and SCN1A and Non-Genetic Variant with Phenotoin Response Phenotype
Employer: Assistant Professor, Chulalongkorn University, Bangkok, Thailand
Katherine Needleman, PhD
Thesis: Exposure-Response Modeling of QT Prolongation for Clinical Studies
Employer: Director, Orphan Products Grants Program, FDA/OOPD
2011
Hyewon Kim, PhD
Thesis: Pharmacometric Modeling and Simulation of Ranitidine in Human Gastric Acid Secretion
Employer: Research Fellow, Federal Drug Administration
2010
Matthew Schaefers, PhD
Thesis: Staphylococcal Toxic Shock Syndrome Toxin-1 Interactions with Human Vaginal Epithelial Cells and Novel Therapeutics
Employer: Post-Doctoral Fellow, Boston Children's Hospital/ Harvard Medical School, Lab of Dr. Gregory Priebe
Kyle Baron, PhD
Thesis: Pharmacometrics, Pharmacodynamics and Dose Optimization of Fludarabine in Nonmyeloablative Hematopoietic Stem Cell Transplantation
Employer: Senior Research Scientist, Metrum Research Group LLC
Lucy Hodge, PhD
Thesis: The Role of Equilibrative Nucleoside Transporters 1 and 2 in the Disposition of Gemcitabine in Cervical Cancer
Employer: Manager, Medical Information, PROSAR
Annie Clark, PhD
Thesis: Development of Intravenous Topiramate for Neuroprotection and Seizure Control in Neonates
Employer: Scientist, Biomarin
Vijay Ivaturi, PhD
Thesis: Intranasal and Rectal Diazepam for Rescue Therapy: Assessment of Pharmacokinetics and Tolerability
Employer: Research Assistant Professor, College of Pharmacy, University of Maryland
Amit Khatri, PhD
Thesis: Pharmacometric Modeling of Anti-Cancer Agents: Application to Gemcitabine, PQIP and Irinotecan
Employer: Associate Principle Pharmacokineticist, AbbVie, North Chicago, IL.
Ahmed Salem, PhD
Thesis: Demonstration of Pharmacometric Applications to Anti-infective Chemotherapy
Employer: Director, Clinical Pharmacology and Pharmacometrics, AbbvieChicago, IL.
Alumni Spotlight: Spring 2019 ECP Gazette
2009
Ying Chi Lin, PhD
Thesis: Anti-Virulence Paradigm for Development of Staphylococcal Therapies
Employer: Assistant Professor, College of Pharmacy, Kaohsiung Medical University, Taiwan
Janel Long-Boyle, PhD
Thesis: Fludarabine and Clofarabine: A Tale of Two Purine Analogs in Allogeneic in Hematopoietic Cell Transplantation (HCT)
Employer: Assistant Professor, College of Pharmacy, Department of Clinical Pharmacy, University of California, San Francisco
Varun Goel, PhD
Thesis: Application of an Active Comparator-Based, Benefit-Risk Assessment in Evaluating Clinical Trial Design Features of a New Chemical Entity Using a Bayesian Decision-Theoretic Framework
Employer: Modeler, Novartis M&S, Novartis, Inc.
2008
Jiayin Huang, PhD
Thesis: Mycophenolate Pharmacokinetics and Pharmacodynamics in Hematopoietic Cell Transplantation
Employer: Senior Clinical Pharmacologist, Vertex, Inc, Cambridge, MA
Baralee Punyawudho (Prasittisopin), PhD
Thesis: Pharmacometrics of Antiepileptic Drugs: Modeling and Simulation-based Studies of Lamotrigine and Carbamazapine Pharmacokinetics
Employer: Assistant Professor, Chulalongkorn University, Bangkok, Thailand
Manisha Lamba, PhD
Thesis: Population Pharmacokinetics and Exposure-Response of Clobazam and Its Active Metabolite
Employer: Clinical Pharmacology Lead, Pfizer, Inc, Groton, CT
2007
Atul Kumar, PhD
Thesis: Impact of surgery and hemorrhagic shock on the pharmacokinetics of cytochrome P450 drug probes
Employer: University of Minnesota
Vikas Kumar, PhD
Thesis: Pharmacogenetics of CYP2C9 inhibition
Employer: Associate Director, Clinical Pharmacology, Pfizer, Inc, Groton, CT
Wonkyung Byon, PhD
Thesis: Population pharmacometric analyses in HIV-infected adults and children: application to zidovudine, lamivudine, indinavir, and efavirenz
Employer: Clinical Pharmacology Lead, Pfizer, Inc, Groton, CT
2006
Lian Wei, M.S.
Thesis: The effect of CYP2C9 genetic polymorphism on reaction coupling and uncoupling
Employer: Vertex, Inc. Cambridge, MA
Pamela Clemens, PhD
Thesis: Alternate routes of Antiepileptic drug administration: A clinical study of rectally administered Oxcarbazepine suspension
Employer: Sr. Director, Clinical Pharmacology, Medical Counter Measures, Johnson and Johnson
Jae Eun Ahn, PhD
Thesis: Pharmacometric characterization of antiepileptic drugs in the elderly
Employer: Assistant Professor, College of Pharmacy, Kangwon National University, Korea
2005
Kathleen Green, M.S.
Thesis: Mycophenolate Mofetil Pharmacology and Bioavailability in Hematopoietic Cell Transplantation for Malignant Diseases
Employer: Fairview Southdale
2004
Matthew Hummel, PhD
Thesis: Assessment of Multiple Substrate Bending in CYP2C9
Employer: Mylan Laboratories
Nitin Kaila, PhD
Thesis: Pharmacometric issues in modeling and simulation: Metoprolol population pharmacokinetics and pharmacodynamics in healthy subjects
Employer: Associate Director, Pharmacometrician, Pfizer, Inc
Juki Ng, PhD
Thesis: Cyclophosphamide pharmacogenetics in breast cancer patients
Employer: Associate Director, Clinical Pharmcokinetics and Pharmacodynamics, Abbott Laboratories, Chicago, IL