Institute of Personalized Medicine - PUMA IPM

Pharmacogenomics aims at understanding how variations in the human genome affect the response to medications.

Our researchers are working to generate new knowledge, and to develop tools and algorithms that can help in personalizing medicine utilizing a patient’s genetic profile and other factors to achieve maximum therapeutic benefit with minimum toxicity.

Pharmacogenomics Conference

Genomic Testing to Individualize Drug Therapy

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June 22, 2018  -  8am-5pm
McNamara Alumni Center
University of Minnesota

News

Catherine McCarty Cathy McCarty was the Principal Investigator for the Marshfield Clinic Personalized Medicine Research Project, with more than twenty genetic epidemiology and pharmacogenetic studies of metformin, coumadin and ACE inhibitors.  She is currently collaborating with Dr.

A College of Pharmacy internal grant has been awarded to the project, "Enhance Comprehensive Pharmacist Services to Improve Patient Health: Creating a 21 st Century Precision Medicine Intensive Care Unit (ICU)."

The focus of the project is on sedation in mechanically ventilated patients and it aims to identify actionable genetic variants in ICU patients and evaluate the relationship between genotypes and drug efficacy as well as adverse drug reactions (ADR) in a real-world setting at the bedside.

The Institute of Personalized Medicine and the Minnesota Precision Medicine Collaborative had a table at the at the Mini Medical School on Oct. 30, 2017. They presented "Precision Medicine and Pharmacogenomics" which included themes on what pharmacogenomics is, and what pharmacogenomic research is being done at the University.

Rui ZhangDr. Zhang is an Assistant Professor in the Department of Pharmaceutical Care & Health System (PCHS) and the Institute for Health Informatics (IHI). He is also a faculty member in Data Science graduate program. Dr. Zhang has extensive education background and research experience in the field of health and biomedical informatics, especially biomedical natural language processing and text mining.

Weekly Genomics Scan

This weekly update features emerging roles of human genomics, testing and interventions in a wide variety of noncommunicable diseases across the life span.

Health Impact Weekly Scan

Summit on Native American & Rural Health

Addressing the Precision Medicine Knowledge Gap

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March 22, 2018
10am-4pm
University of Minnesota Medical School, Duluth campus

Precision Medicine Seminar Series

Presented by The Minnesota Precision Medicine Collaborative

Friday, February 2 
2 PM - 3 PM 
1-450 Moos Tower* (TC); 302 Heller Hall (Duluth, via ITV)

"Panel Discussion: A Vision for Precision Medicine in the AHC"
 
Our panelists will include Jakub Tolar, MD, PhD, Dean of the Medical School and Interim AHC Vice President for Health Sciences; and Clifford Steer, MD, the Medical School's Associate Dean for Industry Partnerships, and others.

CPIC Guideline Videos

See the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Videos, taken from the PharmGKB YouTube channel.

Codeine and CYP2D6

Clopidogrel and CYP2C19

Simvastatin and SLCO1B1

Phenytoin, HLA-B and CYP2C9

Carbamazepine and HLA-B

Allopurinol and HLA-B

Abacavir and HLA-B