Institute of Personalized Medicine - PUMA IPM

Pharmacogenomics aims at understanding how variations in the human genome affect the response to medications.

Our researchers are working to generate new knowledge, and to develop tools and algorithms that can help in personalizing medicine utilizing a patient’s genetic profile and other factors to achieve maximum therapeutic benefit with minimum toxicity.

Pharmacogenomics Conference

Genomic Testing to Individualize Drug Therapy

The 2018 Pharmacogenomics Confernece on June 22 was at capacity with over 310 registrants in attendance.  Topics included: cancer somatic mutations and selection of targeted therapies, emerging PGx areas such as analgesics and how to apply PGx in minority populations, clinical PGx guidelines, use of PGx in children, implementation of PGx in practice settings, insurance reimbursement, and evidence for cost effectiveness and improved quality of care.  Participants were given the opportunity to have personal PGx testing done by OneOme and received their results at check-in.  See speaker information, pictures and videos here.

Stay tuned for information on our next PGx Conference - date TBD.

News

Sam CallistoSamuel is a PhD Candidate in the Experimental and Clinical Pharmacology department. During his time in the program Samuel has pursued various avenues of research related to precision medicine in neuropharmacology with a focus on anti-seizure drugs.

Debra SkaarWelocome to our newest member, Debra Skaar, PharmD, FCCM.  She is an Associate Professor in Experimental and Clinical Pharmacology.  Read her hio here. 

Jay's research focuses on the determination of known genetic variations within Very Important Pharmacogenes (VIPs) in the Hmong population which brings local, state-wide and regional relevance to the nationally supported NIH “Precision Medicine Initiative”.

Robert Straka is a President's Community-Engaged Scholar Award Collegiate Recipient. View a video of his work in the Hmong community.

Weekly Genomics Scan

This weekly update features emerging roles of human genomics, testing and interventions in a wide variety of noncommunicable diseases across the life span.

Health Impact Weekly Scan

CPIC Guideline Videos

See the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Videos, taken from the PharmGKB YouTube channel.

Codeine and CYP2D6

Clopidogrel and CYP2C19

Simvastatin and SLCO1B1

Phenytoin, HLA-B and CYP2C9

Carbamazepine and HLA-B

Allopurinol and HLA-B

Abacavir and HLA-B