Analytical Instruments

Major Analytical Equipment 

Mass Spectroscopy: (7 Systems available)

  • TSQ Quantum Classic LC-MS/MS with Agilent 1200 HPLC with DAD detector
  • TSQ-AM Quantum Classic LC-MS/MS with Agilent 1100 HPLC
  • Sciex API4000 Qtrap LC-MS/MS with a Waters Acquity UPLC
  • Quattro Ultima LC-MS/MS with Acquity UPLC
  • Sciex API4000 LC-MS/MS with Agilent 1100 HPLC
  • Agilent 5973 GC-MSD, with 6890 GC
  • Agilent 5971 GC-MSD, with 5890 GC

High Performance Liquid Chromatography Systems: (3 systems available)

  • Agilent 1100 series HPLC with UV, FLD, DAD and ELCD

Chromatography Software

  • Chromperfect Spirit ®Version 5.5.2
  • Enhanced ChemStation® Version A.03.00
  • LC 3D ChemStation® Version B.03.02
  • Xcalibur® Version 2.07
  • MassLynx® Version 4.1
  • Analyst® Version 1.5

General Laboratory Equipment

  • HT-6 Tissue Homogenizer OPS Diagnostics
  • CAHN Ultra Micro balance
  • Jouan temperature controlled floor centrifuge
  • Sorvall table top centrifuge
  • Zymark sample concentrators
  • Molecular Devices 96 well plate reader
  • Finstrument 96 well plate washer
  • Gilson Fraction Collector
  • Various stir plates, shakers and rockers
  • pH meters
  • Multiple -80 C freezers

Self-Service operation and training

As part of our service to members of the College of Pharmacy the Clinical Pharmacology Analytical Services Laboratory (CPAS) offers operational assistance and training in the use of two LC-MS/MS (see below). Training on these instruments is tailored to the specific needs of the user and can range from simple compound optimization to full training with acquisition software with complete data analysis. The following systems are available.

TSQ Quantum Classic LC-MS/MS

This triple quadrupole mass spectrometer coupled with an Agilent 1200 SL series HPLC and Diode Array detector is ideally suited for quantitation of small molecules. The system is equipped with both ESI (Electrospray ionization) and APCI (Atmospheric Pressure Chemical Ionization) capability. Data reduction with Xcalibur software.

Quattro Ultima LC-MS/MS with Acquity UPLC

This triple quadrupole mass spectrometer is coupled with the Waters Acquity UPLC (Ultra Performance Liquid Chromatography) system ideally suited for handling the latest generation of analytical columns. The system is equipped with both ESI and APCI capability. Data reduction with QuanLynx software.


Individuals interested in training or learning more about these systems should contact Jim Fisher ( or 612-626-4324) for a brief consultation.

Fee schedule: Contact Jim Fisher ( or 612-626-4324) for training and usage rates