Timothy Wiedmann, PhD
Professor Emeritus, Department of Pharmaceutics
Titles
Professor Emeritus, Department of Pharmaceutics
Education
Post-Doctoral Fellowship, Department of Chemistry and Biophysics, University of Virginia
PhD in Pharmaceutics, University of Wisconsin-Madison
MS in Pharmaceutics, University of Wisconsin-Madison
BS in Pharmacy, University of Wisconsin-Madison
Biography
Expertise
- Aerosol
- Cancer chemoprevention
- Liquid crystals
- Lung cancer
- Magnetic targeting
- Respiratory drug delivery
Research Summary
Before his retirement, the research activities of Professor Wiedmann shared the common thread of characterizing the physical chemical properties of colloids, particulate dosage forms, and biological systems for optimizing drug delivery.
Publications
- Yao X, Sabyrov K, Klein T, Penn RL, Wiedmann TS. (2015). Evaluation of magnetic heating of asymmetric magnetite particles. J Magn Magn Mat, 381:21-27. DOI: 10.1016/j.jmmm.2014.12.035
- Wiedmann TS, Naqwi A. (2016). Pharmaceutical salts: Theory, use in solid dosage forms and in situ preparation in an aerosol. Asian J Pharm Sci, 11:722-734. DOI: 10.1016/j.ajps.2016.07.002
- Tǎbǎran AF, O'Sullivan MG, Seabloom DE, Vevang KR, Smith WE, Wiedmann TS, Peterson LA. (2019). Inhaled Furan Selectively Damages Club Cells in Lungs of A/J Mice. Toxicol Pathol, 47(7):842-850. DOI: 10.1177/0192623319869306
- Layek B, Rahman Nirzhor SS, Rathi S, Kandimalla K, Wiedmann TS, Prabha S. (2019). Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery. AAPS PharmSciTech, 20:58. DOI: 10.1208/s12249-018-1288-5
- Olsen TW, Dyer RB, Mano F, Boatright JH, Chrenek MA, Paley D, Wabner K, Schmit J, Chae JB, SellersJT, SinghRJ, Wiedmann TS. (2020). Drug tissue distribution of tudca from a biodegradable suprachoroidal implant versus intravitreal or systemic delivery in the pig model. Transl Vision Sci Tech 9: 11-15. DOI: 10.1167/tvst.9.6.11
- Peterson LA, Oram MK, Flavin M, Seabloom D, Smith WE, O'Sullivan MG, Vevang KR, Upadhyaya P, Stornetta A, Floeder AC, Ho Y-Y, Zhang L, Hecht SS, Balbo S, Wiedmann TS. (2021). Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung. Chem Res Toxicol 34(3):723-732. DOI: 10.1021/acs.chemrestox.0c00350. Epub 2021 Feb 25.
- Peterson LA, Seabloom D, Smith WE, Vevang KR, Seelig DM, Zhang L, Wiedmann TS. (2022). Acrolein Increases the Pulmonary Tumorigenic Activity of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Chem. Res. Toxicol. 35, 10, 1831–1839. DOI: 10.1021/acs.chemrestox.2c00135
- Johnston N, Samuels TL, Goetz CJ, Arnold LA, Smith BC, Seabloom D, Wuertz B, Ondrey F, Wiedmann TS, Vuksanovic N, Silvaggi NR, MacKinnon AC, Miller J, Bock J, Blumin JH. (2022). Oral and Inhaled Fosamprenavir Reverses Pepsin-Induced Damage in a Laryngopharyngeal Reflux Mouse Model. Laryngoscope 133 (Suppl 1):S1-S11. DOI: 10.1002/lary.30242. Epub 2022 Jun 9.