Melanie Nicol, PharmD, PhD

Expertise

HIV and Opportunistic Infections
HIV/AIDS
Clinical Pharmacology
Women's Health
Drug Metabolism and Transport

Awards & Recognition

Deborah E. Powell Center for Women's Health Research Scholar

Professional Associations

Society of Infectious Disease Pharmacists
American Society of Clinical Pharmacology and Therapeutics
American Association of Pharmaceutical Scientists
American College of Clinical Pharmacy

Research Summary

Our research efforts are focused on identifying factors that influence the efficacy of antivirals (and other anti-infectives) in tissue compartments. We are working to describe the penetration of drugs used to treat HIV and related infections into tissue compartments such as the genitals, brain, and lymph tissue. There is a paucity of data on the factors that modulate drug efficacy in tissue compartments yet drug distribution to these tissues is critically important for HIV prophylaxis, suppression of viral shedding, and eradication of viral reservoirs. Our translational lab uses a variety of research approaches with projects spanning in vitro, ex vivo, and clinical studies. We have active studies in both Minnesota as well as Kampala, Uganda.

Teaching

Teaching Areas

Antivirals; Pharmacotherapy of Infectious Disease

Courses

PHAR 6768: Infectious Disease

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