Research demonstrates male birth control pill is ready for human trials

March 28, 2025

Variety of birth control options

Newly published research from Dr. Gunda Georg and the University of Minnesota College of Pharmacy lays the foundation for a hormone-free male birth control pill to enter human clinical trials.

The research, published in Communications Medicine, showed that the oral contraceptive YCT-529 lowered sperm counts in under two weeks in male non-human primates, caused infertility in male mice with a 99% efficacy rate in pregnancy prevention, offered fully-recovered fertility after stopping the drug, and resulted in no detectable side effects. 

Read the full research brief here.

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Media Contacts

Dawn Tucker
College of Pharmacy
Allie Bean
College of Pharmacy
https://www.pharmacy.umn.edu/news/research-demonstrates-male-birth-control-pill-ready-human-trials