Aldrich Lab Research Published in Nature Communications

June 4, 2024

Aldrich Biotin Fig

Prof. Courtney Aldrich and his collaborators recently published an article in Nature Communications on their work with Mycobacterium tuberculosis and biotin synthesis. Their discovery is noteworthy:

"Lipid biosynthesis in the pathogen Mycobacterium tuberculosis depends on biotin for posttranslational modification of key enzymes. However, the mycobacterial biotin synthetic pathway is not fully understood. Here, we show that rv1590, a gene of previously unknown function, is required by M. tuberculosis to synthesize biotin. Our findings open new opportunities to seek BioB inhibitors to treat infections with M. tuberculosis and other pathogens."

The Aldrich Lab has a long history of impactful research on infectious diseases, and we're thrilled to see this important publication in such a high-impact scientific journal.

Congratulations to all of the amazing scientists who worked on this discovery. Way to go!

Read the full article here.

Learn more about the Aldrich group here.

Categories: Research

Tags: Health Sciences

Media Contacts

Dawn Tucker
College of Pharmacy
Eileen Omizo-Whittenberg
College of Pharmacy