Research

Karunya Kandimalla

Research in Pharmaceutics

The design and analysis of drug delivery systems, and investigation of molecular, cellular, and physiological mechanisms underlying absorption, distribution, metabolism, excretion, and pharmacologic effect of drug molecules

Pharmaceutics Faculty Work to Understand and Develop

  • Drug delivery to the central nervous system to treat Alzheimer’s, brain cancer, pain, addiction, and epilepsy
  • Targeted drug delivery to treat cancers
  • Respiratory delivery methods to treat a variety of conditions including lung cancer
  • Engineered nanoparticles to target drugs to the desired sites
  • Polymeric drug delivery
  • Behavior and movement of a drug to its intended destination in the body
  • Materials science and engineering of drug substance and drug products
  • Strategies to enhance drug availability to the body

Facilities

The Pharmaceutics Department is housed in modern facilities within Weaver-Densford Hall of the Academic Health Center on the Minneapolis Campus.

It is well-equipped with a wide range of analytical instrumentation as well as processing equipment. There are also extensive animal facilities for carrying out biopharmaceutical and pharmacokinetic studies. Computer facilities are widely available within the Department, and those in the University Computer Center are also directly accessible.

Weaver-Densford Hall, which houses the College of Pharmacy and School of Nursing, is within a short walking distance of the University Hospital, the Biomedical Engineering Institute, the Institute of Technology (which includes the Department of Chemistry and various departments of engineering), and the two main University libraries, Biomedical (science) and Walter (engineering). Finally, much of the campus is connected by a convenient system of underground passages and skyways.

The Academic Health Center, which includes Pharmacy, Medicine, Dentistry, Nursing, Public Health and Veterinary Medicine, is closely associated in its clinical functions with the teaching hospital at the University of Minnesota Medical Center, located in the heart of the Minneapolis Campus on the East Bank of the Mississippi River, near downtown Minneapolis.

Centers of Research Excellence

In addition to the departmental facilities, the faculty in the Pharmaceutics program participate in interdisciplinary research centers and other research enterprises established at the University of Minnesota. These centers include:

A research services facility of the University of Minnesota, Bioanalytic and Pharmacokinetic Services, which operates under Good Laboratory Practice regulations, exists within the Department of Pharmaceutics. This laboratory acts as an interface with the pharmaceutical industry, performing preclinical and clinical studies on new chemical entities and existing drugs.

Research ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.