Medicinal Chemistry

Medicinal Chemistry structures

Medicinal Chemistry at the U of M

Department of Medicinal Chemistry Faculty work with diverse graduate students, post-doctoral fellows and researchers at the interface of Chemistry and Biology.  Learn more

Medicinal Chemistry

Students on CampusMedicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.

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Research Areas

Medicinal Chemistry professor and student

Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.

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Faculty Spotlight: Courtney Aldrich

courtney aldrichDr. Aldrich received a $3.8 million NIH grant for the project "Siderophore Inhibitors for Tuberculosis that Block Mycobactin Biosynthesis" on which he is the sole PI.  Also, his collaborative research was the focus of a LA times article.

Faculty Spotlight: Natalia Tretyakova

Tretyakova Research GroupDr. Natalia Tretyakova has been named a Distinguished McKnight University Professor.

Faculty Spotlight: Gunda Georg

Dr. Gunda GeorgDr. Gunda Georg’s research towards male contraceptives was featured on several broadcast news outlets including the front page of the Star Tribune.

Research in ITDDInstitute for Therapeutics Discovery & Development

The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.

Congratulations to Kellan Passow, graduate student in the Harki laboratory, who was awarded the American Chemical Society, Minnesota Section Travel Grant! The grant will provide funds for Kellan to attend the Fall 2018 ACS meeting in Boston, Massachusetts where he will make a presentation on his research. 

The research of Dr. Carston Wagner and his lab was featured in a recent Minnesota Daily article titled "UMN Researchers Attacking Cancer Cells with Nanotechnology." The article highlights the Wagner lab's steps towards clinical trials, in discussion with the U.S. Food and Drug Administration, for their nanoring therapy. The nanotherapy modifies the user's own T cells in order to reactivate the immune system to target cancer cells. Unlike other methods to kill tumor cells, the nanoring therapy is reversible and does not carry long-term risks.

Professor Rory Remmel attended the 49th Gordon Research Conference in Drug Metabolism last week at Holderness Academy near Plymouth, New Hampshire. Dr. Swati Nagar (recently promoted to full professor at Temple University) chaired the meeting.  She was a PHD student of Professor Emeritus Cheryl Zimmerman and co-advised by Dr. Remmel.  Three of Dr. Remmel's former PhD students, Vinayak Hosagrahara, Upendra Argikar, and Aaron Teitelbaum were also in attendance.  Dr. Steven Leeder (Minnesota PharmD, 1982) was elected as the academic vice chair. 

Alex Hurben, a graduate student in the Doran lab, has been selected as a trainee for the NIH T32 Chemistry-Biology Interface Training Grant. The grant program allows first-rate students to grow into accomplished professionals both in their primary area of interest and in a complementary field through interdisciplinary research interactions and experiences. Alex will be working with Drs. Doran and Tretyakova to identify harmful oxidation products that drive Alzheimer’s and Parkinson’s disease.


Researcher at Biomedical Discovery District
Research Facilities

Make use of the Department's over 30,000 square feet of modern research laboratory space located within the Academic Health Center and the Biomedical Discovery District.  Read more about our instrumentation, laboratories, facilities and faculty research


Student Spotlight: Sara Coulup

 Graduate student Sara Coulup receives a plaque at the 2018 MIKI meeting for winning the Best Oral Presentation AwardSara Coulup wins the best oral presentation at MIKI 2018.

Student Spotlight: Alex Strom