Medicinal Chemistry

Medicinal Chemistry structures

Medicinal Chemistry at the U of M

Department of Medicinal Chemistry Faculty work with diverse graduate students, post-doctoral fellows and researchers at the interface of Chemistry and Biology.  Learn more

Mission of the Department of Medicinal Chemistry

  • Education and training of scientists of the highest caliber

  • Providing future pharmacy practitioners with the basis for understanding the relationship between molecular structure and the therapeutic, dispositional, and toxicological aspects of drug action

  • Improvement of human health through chemical and biological research

PhD Graduate Program

A diverse education in chemistry and biology that prepares students for the evolving multidisciplinary research of the pharmaceutical industry and academia.

Medicinal Chemistry

Students on CampusMedicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.

Read more about the Department

Research Areas

Medicinal Chemistry professor and student

Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.

Read more about our research

Faculty Spotlight: Courtney Aldrich

courtney aldrichDr. Aldrich received a $3.8 million NIH grant for the project "Siderophore Inhibitors for Tuberculosis that Block Mycobactin Biosynthesis" on which he is the sole PI.  Also, his collaborative research was the focus of a LA times article.

Faculty Spotlight: Natalia Tretyakova

Tretyakova Research GroupDr. Natalia Tretyakova has been named a Distinguished McKnight University Professor.

Faculty Spotlight: Gunda Georg

Dr. Gunda GeorgDr. Gunda Georg’s research towards male contraceptives was featured on several broadcast news outlets including the front page of the Star Tribune.

Research in ITDDInstitute for Therapeutics Discovery & Development

The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.

image of pharmaceutical manufcaturing

The University of Minnesota will join a team of academic institutions, private companies, governmental entities and non-profit organizations across the U.S. as a partner for the newly established National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL). NIIMBL, a public-private partnership supported by a $70M investment from the National Institute of Standards and Technology and at least $129M from other participants, aims to transform biopharmaceutical manufacturing in the U.S.

Gunda Georg

What does it take to get to that moment in a clinic when a doctor gives a patient a compound never before used in modern medicine? The story of Minnelide, an investigational drug for pancreatic cancer patients now in a Phase IA clinical trial at the University of Minnesota, illustrates just how complex and exhilarating that journey can be.

kava plant leaf

New research from the University of Minnesota College of Pharmacy and Masonic Cancer Center has found that consumption of the root of Piper methysticum, or kava, a plant native to the South Pacific Islands, may prevent the development of tobacco smoke-induced lung cancer.

courtney aldrich

Courtney Aldrich, associate professor of medicinal chemistry, has been named editor-in-chief of the American Chemical Society's new, web-only journal ACS Infectious Diseases. With the first issue slated for publication in January 2015, the pioneering journal will meet a growing demand for a place to publish top-notch chemistry-focused infectious diseases research.

Pages

Researcher at Biomedical Discovery District
Research Facilities

Make use of the Department's over 50,000 square feet of modern research laboratory space located within the Academic Health Center and the Biomedical Discovery District.  Read more about our instrumentation, laboratories, facilities and faculty research

Events

Student Spotlight: Jian Tang

 A headshot photo of Jian Tang. He is outside wearing a black t-shirt.  Graduate student Jian Tang of the Harki Laboratory received a 2020-21 Doctoral Dissertation Fellowship.

Student Spotlight: Erik Faber

Medicinal Chemistry Graduate Student Erik Faber

 Erik Faber was selected to receive the 2021 Abul-Hajj/Hanna Exceptional Graduate Student Award in Medicinal Chemistry.