Medicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.
Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.
Faculty Spotlight: Courtney Aldrich
Dr. Aldrich received a $3.8 million NIH grant for the project "Siderophore Inhibitors for Tuberculosis that Block Mycobactin Biosynthesis" on which he is the sole PI. Also, his collaborative research was the focus of a LA times article.
Faculty Spotlight: Natalia Tretyakova
Faculty Spotlight: Gunda Georg
The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.
A paper coauthored by Dr. Natalia Tretyakova on the potential for DNA damage caused by methylating agents was selected as a paper of the month by Environmental Factor, an NIEHS e-publication. Click here to read more about her paper "Histone tails decrease N7-methyl-2′-deoxyguanosine depurination and yield DNA–protein cross-links in nucleosome core particles and cells."
Congratulations to Dr. Todd Doran who is the recipient, along with Dr. Nam Chul Kim, of the 2019 Engebretson Drug Design and Discovery Grant! As awardees they will each receive $15,000 for their project "Development of PINK1 Kinase Inhibitors."
We are saddened to announce the passing of a Medicinal Chemistry alumnus, Dr. Kathy Webster. Kathy graduated with her Ph.D. from the University of Minnesota in 1986 and went on to become the Founding Dean of the Keck Graduate Institute's (KGI) Scool of Pharmacy and Health Sciences. Under her leadership KGI attained accreditation, recruited world-class faculty and staff, and implemented an entirely new active learning curriculum.
An article coauthored by Drs. Natalia Tretyakova and Daeyoon Park on the potential for DNA damage caused by methylating agents was highlighted this month by Chemical & Engineering News. Click here to read more about their paper "Histone tails decrease N7-methyl-2′-deoxyguanosine depurination and yield DNA–protein cross-links in nucleosome core particles and cells."
Make use of the Department's over 30,000 square feet of modern research laboratory space located within the Academic Health Center and the Biomedical Discovery District. Read more about our instrumentation, laboratories, facilities and faculty research.