Medicinal Chemistry

Medicinal Chemistry structures

Medicinal Chemistry at the U of M

Department of Medicinal Chemistry Faculty work with diverse graduate students, post-doctoral fellows and researchers at the interface of Chemistry and Biology.  Learn more

Medicinal Chemistry

Students on CampusMedicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research that leads to the design and development of safe and effective therapeutic, diagnostic, and environmental agents.

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Research Areas

Medicinal Chemistry professor and student

Biosafety/ biosecurity, cancer and neurological drug discovery, chemical neuroscience, chemoprevention and carcinogenesis, combinatorial biosynthesis, computer-aided drug design, drug metabolism, gene therapy, high-throughput screening, immunology, NMR, non-hormonal contraception, peptidomimetics and X-ray crystallography.

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Faculty Spotlight: Courtney Aldrich

courtney aldrichDr. Aldrich received a $3.8 million NIH grant for the project "Siderophore Inhibitors for Tuberculosis that Block Mycobactin Biosynthesis" on which he is the sole PI.  Also, his collaborative research was the focus of a LA times article.

Faculty Spotlight: Natalia Tretyakova

Tretyakova Research GroupDr. Natalia Tretyakova has been named a Distinguished McKnight University Professor.

Faculty Spotlight: Gunda Georg

Dr. Gunda GeorgDr. Gunda Georg’s research towards male contraceptives was featured on several broadcast news outlets including the front page of the Star Tribune.

Research in ITDDInstitute for Therapeutics Discovery & Development

The ITDD carries out interdisciplinary research, helps educate the next generation of scientists, and enhances the biomedical research infrastructure by creating opportunities for drug discovery and early pre-clinical drug development.

An opinion piece written by Emeritus Dean Dr. Marilyn Speedie has been published in the Star Tribune contending that pharmacists are an underutilized resource in the fight against rising prescription drug costs. 

Congratulations to Dr. Michael Walters of the ITDD who was awarded a 5-year R01 grant from the National Institutes of Health with co-PI Dr. Karen Ashe (Neurology) for their project titled “Caspase-2 Probe Compounds.” 

A paper coauthored by Dr. Natalia Tretyakova on the potential for DNA damage caused by methylating agents was selected as a paper of the month by Environmental Factor, an NIEHS e-publication. Click here to read more about her paper "Histone tails decrease N7-methyl-2′-deoxyguanosine depurination and yield DNA–protein cross-links in nucleosome core particles and cells."

Congratulations to Dr. Todd Doran who is the recipient, along with Dr. Nam Chul Kim, of the 2019 Engebretson Drug Design and Discovery Grant! As awardees they will each receive $15,000 for their project "Development of PINK1 Kinase Inhibitors."

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Researcher at Biomedical Discovery District
Research Facilities

Make use of the Department's over 30,000 square feet of modern research laboratory space located within the Academic Health Center and the Biomedical Discovery District.  Read more about our instrumentation, laboratories, facilities and facaulty research

Events

Student Spotlight: Sara Coulup

 Graduate student Sara Coulup receives a plaque at the 2018 MIKI meeting for winning the Best Oral Presentation AwardSara Coulup wins the best oral presentation at MIKI 2018.

Student Spotlight: Alex Strom