Taito O. Soine Lecture

It  is in Professor Soine's memory that the Soine Lecture in Medicinal Chemistry has been established. Through this lecture the department recognized scientists who have made outstanding contributions to medicinal and natural products chemistry.

Ty SoineProfessor Ty Soine was born in Virginia, Minnesota in 1915. He received his B.S. degree in pharmacy in 1938 and his PhD in pharmaceutical chemistry in 1943, both from the University of Minnesota. Following graduation he joined the College of Pharmacy as an instructor and rose through the ranks to full Professor in 1950. Professor Soine chaired the Department of Medicinal Chemistry from 1970 to 1974 and held the position of Assistant Dean for Graduate Studies and Research until his sudden death in 1978.

Professor Soine had a long and distinguished career in medicinal chemistry and natural products chemistry. The scientific community recognized his achievements when he was awarded the AphA Research Achievement Award in Natural Products Chemistry in 1964. Dr. Soine had a lasting influence on the lives of his students and colleagues with whom he shared his warm personality and sense of humor. Those of us who worked with him over the years still remember his subtle wit and his active and dedicated interest in his students.

Recipients by Year

2018
Dr. Ruth Wexler
Bristol-Myers Squibb
"Discovery of Novel Anticoagulants: New Frontiers and Lessons Learned"
 
2016
Dr. Judy Bolton
University of Illinois at Chicago
"Botanicals as Natural Alternatives to Hormone Replacement Therapy: Role in Breast Cancer Prevention"

2014
Dr. James A. Wells
University of California, San Francisco
"Drug Discovery at Challenging Interfaces: the High Hanging Fruit”

2012
Dr. Robert P. Hanzlik
University of Kansas
'Reactive metabolites, cellular targets, & beyond"

2008
Dr. Duane D. Miller
University of Tennessee
"Search for Selective Androgen Receptor Modulators (SARMs)"

2006
Dr. Baldomero M. Olivera
University of Utah
"Conus Peptides: Drug Discovery from Animal Biodiversity"

2005
Dr. Gunda I. Georg
University of Kansas
"A Personal Perspective of Academic Medicinal Chemistry Research in the Past, Present and Future"

2002
Dr. Neal Castagnoli, Jr.
Virginia Tech
"Studies on the Cytochrome P450 and Monoamine Oxidase Catalyzed Oxidation of (Cyclic Allylic) Teriary Amines"

2000
Dr. Garland R. Marshall
Washington University
"Exploring the Interface Between G-Proteins and their Receptors"

1999
Dr. Ralph F. Hirschmann
University of Pennsylvania
"Peptidomimetics: The Synthesis of Unnatural Products: Challenges, Potential and Hazards"

Recipients by Year

1994
Dr. Leroy B. Townsend
University of Michigan
"The Synthesis of Selected Halogenated Benzimidazole Nucleosides and a Discussion on the Role of the Substituent at N1 in Relation to their Biological Activity"

1992
Dr. George L. Kenyon 
University of California, San Francisco
"The Design of Enzyme Inhibitors and DNA Binding Agents Using Shape Complementarity"

1990

Dr. Kuo-Hsiung Lee
University of North Carolina
"Bioactive Natural Products and Analogs as Antitumor, Anti-Malarial, Antifungal, and Anti-Aids Agents"

1988
Dr. Donald T. Witiak
Ohio State University
"ACI-Reductones: Compounds of Interest in the Study of Atherogenic Mechanisms"

1987
Dr. Arthur D. Broom
University of Utah
"Probes of the Thymidylate Synthase Active-Site"

1984
Dr. Mathias P. Mertes
University of Kansas
"Cofactor Activation in the Design of K-Cat Inhibitors"

1982
Dr. Joseph G. Cannon
University of Iowa
"Structure-Activity Studies of Dopamine Congeners Related to Ergoline"

1981
Dr. Raymond E. Counsell
University of Michigan Medical School
"Approaches to the Site-Specific Delivery of Lipid-Soluble Agents"

1980
Dr. Howard J. Schaeffer
Burroughs Wellcome
"The Chemistry and Biochemistry of Antiviral Agents"

1979
First Soine Lecture
Dr. John A. Montgomery
Southern Research Institute
"Adventures in Purine Nucleoside Chemistry and Biology"