Graduate Faculty
Professor
612-625-7956
aldri015@umn.edu
Research interests: Antibiotics, tuberculosis, synthesis, enzymology
Associate Professor
612-626-2387
ambrose@umn.edu
Associate Professor
612 625-2580
carlsone@umn.edu
Research Interests: Chemical biology, infectious disease, bacterial imaging, proteomics, inhibitor development, natural products
Distinguished McKnight Professor & Merck Professor
612-624-0544
diste001@umn.edu
Research interests: Bioorganic chemistry, enzymology, organic synthesis, protein prenylataion, sesquiterpene biosynthesis, rubber biosynthesis, protein labeling and immobilization, photoaffinity labeling, caged substrates.
Assistant Professor
612-625-9335
doran@umn.edu
Research Interests: Understanding the molecular-level events that underlie neurodegenerative diseases like Alzheimer’s and Parkinson’s disease.
Professor
612-626-2601
ferguson@umn.edu
Research interests: Quantum mechanics, molecular mechanics/dynamics, computer graphics techniques, molecular interactions, investigation of inter- and intramolecular interactions to gain insight for drug design and protein engineering
Professor
612-626-5979
finze007@umn.edu
Research interests: Molecular characterization of protein-drug interactions employing X-ray crystallography. Discovery of novel antimicrobial and therapeutic agents using structure-based design. Protein structure data-mining.
Regents Professor and Head
612-626-6320
georg@umn.edu
Research interests: Design, synthesis, and evaluation of synthetic and natural product-derived medicinal agents; drug discovery by HTS; new synthetic methods; combinatorial chemistry. Therapeutic areas: cancer, male contraception, Alzheimer's disease.
Associate Professor and Director of Graduate Studies
612-625-8687
daharki@umn.edu
Research interests: Synthesis, biophysical characterization, and biological efficacy evaluation of novel small molecules that influence cellular function. Applications for these molecules range from anticancer drug discovery to new tools for modern biotechnology research.
Professor & Philip S. Portoghese Endowed Chair in Chemical Neuroscience, Associate Department Head
612-626-9262
chaskell@umn.edu
Research interests: Peptide Chemistry, Medicinal Chemistry, G-protein Coupled Receptor (GPCR) Pharmacology, Human Receptor Polymorphisms, Neuroscience, Voluntary Exercise of Mice, Obesity, Diabetes, Feeding Behavior
Wallin Land Grant Professor of Cancer Prevention
612-624-7604
hecht002@umn.edu
Research interests: Mechanism by which carcinogens are metabolically activated and detoxified in humans, cancer prevention, nitosamines, aldehydes, and polycyclic aromatic hydrocarbons
College of Science and Engineering Distinguished Professor, Distinguished University Teaching Professor
612-625-1891
hoyex001@umn.edu
Research interests: Organic synthesis, natural products, analogs and prodrugs, symmetry concepts, organometallic chemistry,NMR spectroscopy
Professor
612-626-0164
peter431@umn.edu
Research interests: Genotoxic and nongenotoxic mechanisms by which chemicals initiate cancer
Associate Professor
612-625-0921
pierre@umn.edu
Research interests: Imaging; MRI; diagnostics; infectious diseases
Associate Professor, McKnight Land Grant Professor, McKnight Presidential Fellow
612-624-9091
wcp@umn.edu
Research interests: Inhibitor discovery; protein-protein interactions
Distinguished Professor
612-624-9174
porto001@umn.edu
Research interests: G protein-coupled receptors; molecular recognition; opioid receptors; bivalent ligands; affinity labels
Distinguished Teaching Professor
612-624-0472
remme001@umn.edu
Research interests: Drug metabolism and disposition, evaluation of antiviral drug combinations, metabolic interactions of antiepileptic drugs in the elderly
Professor
612-624-9465
shier001@umn.edu
Research interests: Development of novel non-viral vector transfection agents for use in human gene therapy, strategies for eliminating carcinogenic and estrogenic mycotoxins from the human food supply, exploration of the drug potential of betulins and other natural products
Distinguished McKnight University Professor
612-626-3432
trety001@umn.edu
Research interests: Structural basis for promutagenic and anticancer activity of DNA-modifying agents, DNA damage by tobacco carcinogens and lung cancer, DNA-DNA and DNA-protein cross-linking agents as carcinogens and drugs, DNA oxidation by endogenous reactive oxygen species
Professor and Endowed Chair in Medicinal Chemistry
612-625-2614
wagne003@umn.edu
Research interests: Chemical Biology, design and development of targeted drug delivery approaches, design and study of chemical inducers of protein oligomerization, mechanistic and structural studies of biocatalyis and protein translation