Graduate Faculty

Courtney Aldrich, PhD
Professor

612-625-7956
aldri015@umn.edu

Research interests: Antibiotics, tuberculosis, synthesis, enzymology

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Elizabeth A. Ambrose, PhD
Associate Professor

612-626-2387
ambrose@umn.edu

Research Interests: Biological and Chemical Warfare Agent Mitigation,BSL-2, BSL-3 and Select Agent Research, Homeland Security, High-Throughput and Fragment Screening, Lead Optimization, Psychiatric Pharmacy and Neuropharmacology

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Erin Carlson, PhD
Associate Professor

612 625-2580
carlsone@umn.edu

Research Interests: Chemical biology, infectious disease, bacterial imaging, proteomics, inhibitor development, natural products

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Sunil David, MD, PhD
Professor

612-625-3317
sdavid@umn.edu

Research Interests: Sunil David's research focuses on the discovery and development of endotoxin-sequestering molecules as potential anti-sepsis agents, modulation of innate immune pathways, and host responses to infectious agents.

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Mark Distefano, PhD
Distinguished McKnight Professor & Merck Professor

612-624-0544
diste001@umn.edu

Research interests: Bioorganic chemistry, enzymology, organic synthesis, protein prenylataion, sesquiterpene biosynthesis, rubber biosynthesis, protein labeling and immobilization, photoaffinity labeling, caged substrates.

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Todd Doran, PhD
Assistant Professor

612-625-9335
doran@umn.edu

Research Interests: Understanding the molecular-level events that underlie neurodegenerative diseases like Alzheimer’s and Parkinson’s disease.

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David Ferguson, PhD
Professor

612-626-2601
ferguson@umn.edu

Research interests: Quantum mechanics, molecular mechanics/dynamics, computer graphics techniques, molecular interactions, investigation of inter- and intramolecular interactions to gain insight for drug design and protein engineering

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Barry Finzel, PhD
Professor and Director of Graduate Studies

612-626-5979
finze007@umn.edu

Research interests: Molecular characterization of protein-drug interactions employing X-ray crystallography. Discovery of novel antimicrobial and therapeutic agents using structure-based design. Protein structure data-mining.

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Gunda Georg, PhD
Regents Professor and Head

612-626-6320
georg@umn.edu

Research interests: Design, synthesis, and evaluation of synthetic and natural product-derived medicinal agents; drug discovery by HTS; new synthetic methods; combinatorial chemistry. Therapeutic areas: cancer, male contraception, Alzheimer's disease.

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Daniel Harki, PhD
Associate Professor

612-625-8687
daharki@umn.edu

Research interests: Synthesis, biophysical characterization, and biological efficacy evaluation of novel small molecules that influence cellular function. Applications for these molecules range from anticancer drug discovery to new tools for modern biotechnology research.

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Carrie Haskell-Luevano, PhD
Professor & Philip S. Portoghese Endowed Chair in Chemical Neuroscience, Associate Department Head

612-626-9262
chaskell@umn.edu

Research interests: Peptide Chemistry, Medicinal Chemistry, G-protein Coupled Receptor (GPCR) Pharmacology, Human Receptor Polymorphisms, Neuroscience, Voluntary Exercise of Mice, Obesity, Diabetes, Feeding Behavior

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Stephen Hecht, PhD
Wallin Land Grant Professor of Cancer Prevention

612-624-7604
hecht002@umn.edu

Research interests: Mechanism by which carcinogens are metabolically activated and detoxified in humans, cancer prevention, nitosamines, aldehydes, and polycyclic aromatic hydrocarbons

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Thomas Hoye, PhD
College of Science and Engineering Distinguished Professor, Distinguished University Teaching Professor

612-625-1891
hoyex001@umn.edu

Research interests: Organic synthesis, natural products, analogs and prodrugs, symmetry concepts, organometallic chemistry,NMR spectroscopy

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Lisa Peterson, PhD
Professor

612-626-0164
peter431@umn.edu

Research interests: Genotoxic and nongenotoxic mechanisms by which chemicals initiate cancer

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Valerie Pierre, PhD
Associate Professor

612-625-0921
pierre@umn.edu

Research interests: Imaging; MRI; diagnostics; infectious diseases

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William Pomerantz, PhD
Associate Professor, McKnight Land Grant Professor, McKnight Presidential Fellow

612-624-9091
wcp@umn.edu

Research interests: Inhibitor discovery; protein-protein interactions

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Philip Portoghese, PhD
Distinguished Professor

612-624-9174
porto001@umn.edu

Research interests: G protein-coupled receptors; molecular recognition; opioid receptors; bivalent ligands; affinity labels

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Rory Remmel, PhD
Distinguished Teaching Professor

612-624-0472
remme001@umn.edu

Research interests: Drug metabolism and disposition, evaluation of antiviral drug combinations, metabolic interactions of antiepileptic drugs in the elderly

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W. Thomas Shier, PhD
Professor

612-624-9465
shier001@umn.edu

Research interests: Development of novel non-viral vector transfection agents for use in human gene therapy, strategies for eliminating carcinogenic and estrogenic mycotoxins from the human food supply, exploration of the drug potential of betulins and other natural products

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Natalia Tretyakova, PhD
Distinguished McKnight University Professor

612-626-3432
trety001@umn.edu

Research interests: Structural basis for promutagenic and anticancer activity of DNA-modifying agents, DNA damage by tobacco carcinogens and lung cancer, DNA-DNA and DNA-protein cross-linking agents as carcinogens and drugs, DNA oxidation by endogenous reactive oxygen species

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Carston Wagner, PhD
Professor and Endowed Chair

612-625-2614
wagne003@umn.edu

Research interests: Chemical Biology, design and development of targeted drug delivery approaches, design and study of chemical inducers of protein oligomerization, mechanistic and structural studies of biocatalyis and protein translation

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