While enrolled in the graduate program in Experimental and Clinical Pharmacology students will strive, with faculty and staff, to advance the science of human pharmacology and therapeutics while maintaining the highest standards of ethics in research and education.

Graduate Program Coursework

Degree Requirements

Degree Requirements

Requirements for PHD

The PhD degree requires core graduate credits, a minimum of 24 course credits and 24 doctoral thesis credits. Students design their program with the guidance of their advisors.

Students must pass one written preliminary examination and one preliminary oral examination before writing the dissertation. The final oral examination for the PhD is a defense of the thesis. This must be done within five calendar years after passing the preliminary oral examination.

Requirements for the M.S. Degree

The M.S. Degree has three required courses and the remainder of the program is designed with the guidance of the advisor, which includes:

  • Additional academic course work (at least nine additional credits). Courses are determined by the student and advisor. 
  • Two papers of publishable quality; one paper must include a research component in which there is analysis of data.
  • A final oral examination for degree completion. The basis of the oral exam is defense of the M.S. Degree papers.

PhD Core Courses and Emphasis Areas

PhD Core Courses and Emphasis Areas

Required Courses

ECP 5220: Regulatory Issues in Drug Research (1 credit)
ECP 8100: Seminar (1 credit repeated, maximum 4 credits)
ECP 8230: Clinical Therapeutics
ECP 8992: Readings ( 1 credit repeated, maximum 8 credits)
ECP 8888: Thesis Credit (24 credits)

Potential Areas of Emphasis (6 credits)

Drug Metabolism Emphasis
ECP 5620 Drug Metabolism and Disposition (3 credits)
PubH 6160 Metabolomics (3 credits)
PubH 6450 Biostatistics 1 (4 credits)
PubH 6451 Biostatistics II (2 credits)
BioC 5001 Biochemistry (5 credits)
MedC 8600 Chemical Aspects of Metabolism and Bioactivism (2 credits)
Phar 6163 Pharmacokinetics
Phar 6224 Pharmacogenomics

Phm 8421 Advanced Pharmacokinetics

Experimental Pharmacotherapeutics Emphasis
PubH 6450 Biostatistics 1 (4 credits)
PubH 6451 Biostatistics II (4 credits)
PubH 7420 Clinical Trials: Design, Implementation and Analysis (3 credits)

Infectious Diseases Emphasis
ECP 5620 Drug Metabolism and Disposition (3 credits) 
PHAR 6224 Pharmacogenomics (2 credits)
PUBH 7420 Clinical Trials (3 credits) 
PubH 6450 Biostatistics 1 (4 credits)
PubH 6451 Biostatistics II (4 credits)
MICA 8010 Microbial Pathogenesis (3 credits)
MICA 8002 Structure and Function of Bacteria and Virus (4 credits)
MICA 8371 Mucosal Immunobiology (3 credits)

Without PharmD Degree
PHAR 6163 Pharmacokinetics (3 credits)
PHAR 6156 Medicinal Agents III: Antimicrobial Agents (4 credits)
NURS 5228 Pharmacology for Advanced Practice Nursing (2 credits)

Pharmacogenomics Emphasis
ECP 8900 Genomics ReadingsPhar 6224 Pharmacogenomics (2 credits)
PubH 6381 Genetics (2 credits)
PubH 6450 Biostats I (4 credits)
PubH 6451 Biostats II (4 credits
GCD 4034 Molecular Genetics (3 credits)

Pharmacometrics Emphasis
ECP 8400 Pharmacometrics (3 credits)
ECP 8410 Population Pharmacokinetic Modeling (2 credits)
ECP 8420 Clinical Trials Simulation (2 credits)
ECP 8430 Advances in Pharmacometric Modeling and Simulation (1 credit)
PubH 6420 Introduction to SAS Programming (1 credit)
PubH 7420 Clinical Trials (3 credits)
PubH 7430 Correlated Data (3 credits)
PubH 7440 Introduction to Baysian (3 credits)
PubH 7450 Survival Analysis (3 credits)
PubH 7470 Statistics for Translational Research (3 credits)
Stat 5101 Theory of Statistics I (4 credits)
Stat 5102 Theory of Statistics II (4 credits)
Stat 5302 Applied Regression Analysis (4 credits)
Stat 5303 Designing Experiments (4 credits
Stat 5401 Multivariate (3 credits)

Course Descriptions

Course Descriptions

ECP Thesis Credit Courses

ECP 8444: FTE: Doctoral.

ECP 8777: Thesis Credits: Master's (1-18 credits).

ECP 8888: Thesis Credits: Doctoral (1-24 credits).

ECP Courses

ECP 5220: Regulatory Issues in Drug Research.

ECP 5620: Drug Metabolism and Disposition. Oxidative/conjugative enzymes systems involved in human drug metabolism/disposition. Various in vitro models used to evaluate drug metabolism or chemical entity, pros/cons of each. Factors involved in conducting in vivo studies. Components used to predict in vivo drug disposition from in vivo studies.

ECP 8100: Seminar. Discussion of contemporary issues and research problems in the areas of experimental and clinical pharmacology.

ECP 8200: Research problems. An individually designed research experience directed at contemporary problems related to the drug use process.

ECP 8220: Experimental and Clinical Pharmacology. Theory of advanced methodologies, applications and evaluation techniques used to determine efficacy and toxicity of new drug therapies. Advanced techniques for collecting and evaluating data.

ECP 8230: Advanced Topics in Experimental and Clinical Pharmacology. This is usually taught by individuals who have an area of research in a particular topic. Example topics include: Pharmacometrics, Pharmacogenomics, Neuropharmacology.

ECP 8500: Advances in Pharmacometric Modeling and Simulation.

ECP 8501: Pharmacometrics. Theory and application of contemporary methods for analysis of concentration-time data and exposure-response relationships.

ECP 8502: Population Pharmacokinetic Modeling. The pharmacokinetics and pharmacodynamics of a drug in a population are frequently analyzed using nonlinear mixed-effects model. This course will present the theoretical background for using a mixed effects model in a population analysis and describe the process of building fixed and random effects into a pharmacostatistical model. A project will allow the student to become familiar with a contemporary population pharmacokinetic analysis program.

ECP 8503: Intermediate Population PK/PD Methods. Present the theory and hands-on application of intermediate population methods using nonlinear mixed-effects model applied to pharmacologic systems.

ECP 8504 Modeling Biologics. Develop computer skills to apply nonlinear regression models to describe the pharmacokinetics and pharmacodynamics of biologics.

ECP 8506: Clinical Trial Simulation. Theory/application of contemporary methods of using simulations to design more efficient/informative clinical trials.

ECP 8490: Advanced Topics in Pharmacometrics. Discussion and critical evaluation of new techniques, issues and philosophies relating to Pharmacometrics that have appeared in recent literature or at scientific/professional meetings.