Alumni

2017

Ali Alhadab, PhD
Thesis: The Utility of Pharmacometrics in Drug Development and Pharmacotherapy of Antimicrobials
Employer: Pfizer

David Hottman, PhD
Thesis: The Role of High-Density Lipoproteins and Related Pathways in Alzheimer’s Disease
Employer: University of Minnesota

Taraswi Mitra Gosh, PhD
Thesis: Pharmacogenomics of Chemotherapeutic Agents: Carboplatin and Paclitaxel
Employer: University of Minnesota

Cristina Peterson, PhD
Thesis: Alleviation of Chronic Neuropathic Pain by Agmatine Requires the GluN2B Subunit of the NMDA Receptor
Employer: University of Minnesota

Youssef Roman, PhD
Thesis: Pharmacogenetic Investigations Using Community-Based Participatory Research to Address Health Disparities in Minnesota Hmong
Employer: University of Hawaii

2016

Mariam Ahmed, PhD
Thesis: Application of Pharmacometrics to Rare Diseases
Employer: United States Food and Drug Administration

Chay Lim, PhD
Thesis: Application of Quantitative Pharmacological Modeling to Improve Drug Therapy in Older Adults
Employer: Pfizer

Kinjal Sanghavi, PhD
Thesis: Personalizing Therapy in Transplantation: Focus on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Drugs Used in Hematopoeitic Stem Cell and Kidney Transplant
Employer: Bristol-Myers Squibb

2015

Neha Bhise, PhD
Thesis: MicroRNAs As Predictors of Nucleoside Analog Sensitivity in Acute Myeloid Leukemia

Caroline Churchill, PhD
Thesis: The Impace of Gene Transfer of Arginine Decarboxylase to the Central Nervous System on Opioid Analgesic Tolerance
Employer: University of Minnesota

Aaron Gillman, PhD
Thesis: Vaccination and Host-Targeted Interventions for Staphylococcus aureus Exotoxin-Mediated Diseases.
Employer: Arctic University of Norway

Malek Okour, PhD
Thesis: The Pharmacokinetics of Enterohepatic Circulation

Krista Sands, PhD
Thesis: Characterization of the Relationship Between Whole Blood and Plasma Topiramate Concentrations.
Employer: University of Minnesota

Harrison Tam, PhD
Thesis: The Effect of Obesity and High-Fat Diet on Cardiovascular Risk and Intestinal Drug Metabolism
Employer: University of Kentucky

2014

Mary Holmay, PhD
Thesis:N- acrtylcysteine: pharmacokinetics and effects in selected neuro degenerative disorders
Employer: Upsher-Smith, Minneapolis, MN

Suresh Agarwal, PhD
Thesis: Clinical Pharmacology and Pharmacometric Analyses of CNS Drugs Used in the Acute Management of Seizures and Spasticity
Employer: AbbVie, Inc, Chicago, IL

Jie Zhou, PhD
Thesis: Mitigating Oxidative Stress in Childhood Cerebral Adrenoleukodystrophy – An Investigation of N-acetylcysteine Pharmacology
Employer: Pharmacokineticist, Nuventra Pharma Sciences

2013

Jia Kang, MS, PhD
Thesis: Pharmacometric Analyses of drug exposure and response data
Employer: Research Scientist, Pharmacometrics at Metrum Research Group LLC

Manoj Chiney, PhD
Thesis: Effect of obesity on hepatic drug metabolism
Employer: Research Investigator, Bristol-Myers Squibb

Gavin Bart, PhD
Thesis: Methadone Population Pharmacokinetics: Toward understanding the dose-response relationship in the treatment of opiate addition
Employer: Division Director of Addictive Medicine, Hennepin County Medical Center, Minneapolis, MN

2012

Chaitali Passey, PhD
Thesis: Application of pharmacometrics for covariate selection and dose optimization of tacrolimus in adult kidney transplant recipients
Employer: Research Investigator, Bristol Myer Squibb, Oncology/Immunology Division, New Jersey

Ghada F. Ahmed, PhD
Thesis: Pharmacometric Analyses of Anti-epileptic Drugs in Elderly Patients: Applications to Carbamazepine, Gabapentin and Topiramate
Employer: Senior Clinical Pharmacokineticist, Abbott Laboratories, No. Chicago, IL

Akshanth Polepally, PhD
Thesis: Pharmacometric Analyses of Lamotrigine in Special Populations: Application to Pregnant Women, Younger Adult and Elderly Epilepsy Patients
Employer: Senior Clinical Pharmacokineticist, AbbVie Inc., Chicago, IL

Azher Arafah, PhD
Thesis: Studies investigating the impact of select genotypes on the pharmacological effect of fenofibrate
Employer: Assistant Professor, Clinical Pharmacy Department, College of Pharmacy King Saud University, Saudi Arabia

Heather Vezina, PhD
Thesis: Application of Pharmacometric Methods to Studies of Antiviral Prophylaxis After Solid Organ Transplantation
Employer: Research Investigator, Bristol-Myers Squibb

Pornpimol Kijsanayotin PhD
Thesis: Association of Genetic Variants in CYP ARCB1 and SCN1A and Non-Genetic Variant with Phenotoin Response Phenotype
Employer: Assistant Professor, Chulalongkorn University, Bangkok, Thailand

Katherine Needleman, PhD
Thesis: Exposure-Response Modeling of QT Prolongation for Clinical Studies
Employer: Director, Orphan Products Grants Program, FDA/OOPD

2011

Hyewon Kim, PhD
Thesis: Pharmacometric Modeling and Simulation of Ranitidine in Human Gastric Acid Secretion
Employer: Research Fellow, Federal Drug Administration

2010

Matthew Schaefers, PhD
Thesis: Staphylococcal Toxic Shock Syndrome Toxin-1 Interactions with Human Vaginal Epithelial Cells and Novel Therapeutics
Employer: Post-Doctoral Fellow, Boston Children's Hospital/ Harvard Medical School, Lab of Dr. Gregory Priebe

Kyle Baron, PhD
Thesis: Pharmacometrics, Pharmacodynamics and Dose Optimization of Fludarabine in Nonmyeloablative Hematopoietic Stem Cell Transplantation
Employer: Senior Research Scientist, Metrum Research Group LLC

Lucy Hodge, PhD
Thesis: The Role of Equilibrative Nucleoside Transporters 1 and 2 in the Disposition of Gemcitabine in Cervical Cancer
Employer: Manager, Medical Information, PROSAR

Annie Clark, PhD
Thesis: Development of Intravenous Topiramate for Neuroprotection and Seizure Control in Neonates
Employer: Clinical Research Scientist, Upsher-Smith Laboratories, Inc.

Vijay Ivaturi, PhD
Thesis: Comparison of Model-Based Approaches to Assess QTc Liability During First Time in Human (FTIH) Studies
Employer: Research Assistant Professor, Department of Pharmacy Practice and Science, Center for Translational Medicine, University of Maryland School of Pharmacy

Amit Khatri, PhD
Thesis: Pharmacometric Modeling of Anti-Cancer Agents: Application to Gemcitabine, PQIP and Irinotecan
Employer: Associate Principle Pharmacokineticist, AbbVie, North Chicago, IL.

Ahmed Salem, PhD
Thesis: Demonstration of Pharmacometric Applications to Anti-infective Chemotherapy
Employer: Associate Principle Scientist, Abbott Laboratories, North Chicago, IL.

2009

Ying Chi Lin, PhD
Thesis: Anti-Virulence Paradigm for Development of Staphylococcal Therapies
Employer: Assistant Professor, College of Pharmacy, Kaohsiung Medical University, Taiwan

Janel Long-Boyle, PhD
Thesis: Fludarabine and Clofarabine: A Tale of Two Purine Analogs in Allogeneic in Hematopoietic Cell Transplantation (HCT)
Employer: Assistant Professor, College of Pharmacy, Department of Clinical Pharmacy, University of California, San Francisco

Varun Goel, PhD
Thesis: Application of an Active Comparator-Based, Benefit-Risk Assessment in Evaluating Clinical Trial Design Features of a New Chemical Entity Using a Bayesian Decision-Theoretic Framework
Employer: Modeler, Novartis M&S, Novartis, Inc.

2008

Jiayin Huang, PhD
Thesis: Mycophenolate Pharmacokinetics and Pharmacodynamics in Hematopoietic Cell Transplantation
Employer: Senior Clinical Pharmacologist, Vertex, Inc, Cambridge, MA

Baralee Punyawudho (Prasittisopin), PhD
Thesis: Pharmacometrics of Antiepileptic Drugs: Modeling and Simulation-based Studies of Lamotrigine and Carbamazapine Pharmacokinetics
Employer: Assistant Professor, Chulalongkorn University, Bangkok, Thailand

Manisha Lamba, PhD
Thesis: Population Pharmacokinetics and Exposure-Response of Clobazam and Its Active Metabolite
Employer: Clinical Pharmacology Lead, Pfizer, Inc, Groton, CT

2007

Atul Kumar, PhD
Thesis: Impact of surgery and hemorrhagic shock on the pharmacokinetics of cytochrome P450 drug probes
Employer: University of Minnesota

Vikas Kumar, PhD
Thesis: Pharmacogenetics of CYP2C9 inhibition
Employer: Associate Director, Clinical Pharmacology, Pfizer, Inc, Groton, CT

Wonkyung Byon, PhD
Thesis: Population pharmacometric analyses in HIV-infected adults and children: application to zidovudine, lamivudine, indinavir, and efavirenz
Employer: Clinical Pharmacology Lead, Pfizer, Inc, Groton, CT

2006

Lian Wei, M.S.
Thesis: The effect of CYP2C9 genetic polymorphism on reaction coupling and uncoupling
Employer: Vertex, Inc. Cambridge, MA

Pam Clemens, PhD
Thesis: Alternate routes of Antiepileptic drug administration: A clinical study of rectally administered Oxcarbazepine suspension
Employer: Associate Scientific Director, Biologics, Clinical Pharmacology, Oncology at Janssen, Pharmaceutical Companies of Johnson and Johnson

Jae Eun Ahn, PhD
Thesis: Pharmacometric characterization of antiepileptic drugs in the elderly
Employer: Assistant Professor, College of Pharmacy, Kangwon National University, Korea

2005

Kathleen Green, M.S.
Thesis: Mycophenolate Mofetil Pharmacology and Bioavailability in Hematopoietic Cell Transplantation for Malignant Diseases
Employer: Fairview Southdale

2004

Matthew Hummel, PhD
Thesis: Assessment of Multiple Substrate Bending in CYP2C9
Employer: Mylan Laboratories

Nitin Kaila, PhD
Thesis: Pharmacometric issues in modeling and simulation: Metoprolol population pharmacokinetics and pharmacodynamics in healthy subjects
Employer: Associate Director, Pharmacometrician, Pfizer, Inc

Juki Ng, PhD
Thesis: Cyclophosphamide pharmacogenetics in breast cancer patients
Employer: Associate Director, Clinical Pharmcokinetics and Pharmacodynamics, Abbott Laboratories, Chicago, IL