Curbside Consult Volume 18, Issue 4 - Fourth Quarter 2020

Research Updates 

Candesartan versus Lisinopril on Neurocognitive Function in Older Adults with Mild Cognitive Impairment
Bridget Williams, Pharm.D., Allina Health
Does antihypertensive therapy provide protective effects on cognitive function in patients with hypertension and mild cognitive impairment? Candesartan and lisinopril go head-to-head in a battle of wits.

The HPV Vaccine and The Associated Risk of Developing Invasive Cervical Cancer
Athena Cannon, PharmD., Pharmaceutical Care Leadership Residency - Broadway Family Medicine
Does this large scale study support our current understanding of the HPV vaccine’s association with decreasing cervical cancer?

Colchicine in Patients with Chronic Coronary Disease
Radhika Patel, PharmD., Minnesota Community Care
Learn about the potential benefits of colchicine in lowering the cardiovascular risk in individuals with chronic coronary disease.

Therapeutic Thoughts

First-line Pharmacotherapy for Smoking Cessation with Comorbid Psychiatric Conditions
Ashley Jensen, Pharm.D., New Ulm Medical Center
A now-removed black box warning for neuropsychiatric effects of varenicline led physicians and patients to be reluctant to use this medication. The American Thoracic Society and American College of Cardiology provide updated information on the use of varenicline as first-line therapy for those with comorbid mental health conditions.

Cardiovascular Risk Reduction in Type 2 Diabetes
Lauren Martens, PharmD., CentraCare St. Cloud
See how the recently released American College of Cardiology 2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients with Type 2 Diabetes compares to the 2020 American Diabetes Association Standards of Medical Care in Diabetes in regard to recommended therapies for patients with concurrent cardiovascular disease and other common comorbid conditions.

From the Pharmacy Press  

Risk Factors for Genitourinary Infections with SGLT-2 Inhibitors
David Bunch, Pharm.D., Geritom Medical Inc.
What effect do A1c and other baseline factors have on the risk for genitourinary infections when starting an SGLT2 inhibitor? Here are some things you should take into consideration.

A Call to Action- Pharmacists’ role and responsibility regarding systemic racism
Emily Evan, PharmD., Community-University Health Care Center
Structural racism has many implications throughout society, including within healthcare. What is the pharmacist’s role in addressing and dismantling systemic racism, and where do we start?

Implementation of Primary Care Clinical Pharmacy Services for Adults Experiencing Homelessness
Anna Insley, PharmD., Welia Health
An estimated 500,000 people or more experience homelessness on any given night in the United States. Read on to find out how clinical pharmacists can have an impact on this health disparity.

Miscellaneous News  

FDA Updates on Black Box Warnings
Sami Russo, PharmD., Goodrich Pharmacy
In recent months, black box warnings have been updated for several drugs commonly seen in primary care practice including, Invokana®️ (canagliflozin), benzodiazepines, and non-steroidal inflammatory drug (NSAID) use in pregnancy.

Comprehensive Medication Review: New Poll Indicates Interest but Low Receipt Among Older Adults
Caitlin Pederson, Pharm.D., M Health Fairview
Comprehensive medication reviews (CMRs) as a part of Medication Therapy Management (MTM) have been shown to help resolve problems associated with polypharmacy. Learn how frequently Medicare Part D patients utilize this beneficial program offered by their insurance plans.

Flu, Pneumonia Vaccinations Tied to Lower Risk of Alzheimer’s Dementia
Caitlin Pederson, Pharm.D., M Health Fairview
Prior studies have suggested that influenza and pneumonia vaccination may prevent cognitive decline. New, larger studies may further support this claim.