Curbside Consult Volume 16, Issue 4 - Fourth Quarter 2018

Research Updates 

Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Adults
Kristen Schroeder, Pharm.D., St. Cloud VA
Statin prescribing for older patients is increasing, but do statins confer primary prevention benefit for those age 75 years and older?

The Role of Vitamin D Levels in Patients with Painful Diabetic Neuropathy
Rebekka Schrecengost, Pharm.D., Essentia Health
Should symptoms of painful diabetic neuropathy prompt a serum vitamin D level? A recent study investigates the correlation between the severity of diabetic peripheral neuropathy and vitamin D levels.

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients
Kaity Bader, Pharm.D., Apple Valley Medical Clinic, Fairview Physician Associates
Lorcaserin is an effective medication for weight management in conjunction with dietary changes and increased physical activity, but what about cardiovascular safety and efficacy? The CAMELLIA-TIMI 61 has the answers!

Therapeutic Thoughts

Updated Guidelines for Management of Hyperglycemia in Type 2 Diabetes
Charlie Sieberg, Pharm.D., New Ulm Medical Center
New recommendations outline type 2 diabetes treatment options in the context of comorbidities and patient specific factors. Where do sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA) fit in?

Aspirin for Primary Prevention
Tiffany Cheng, Pharm.D., Fairview Pharmacy Services
Old Drug, New Evidence: Aspirin Therapy for Primary Prevention

A Closer Look at the Updated 2018 Chest Guidelines Expert Panel on Atrial Fibrillation
Sarah Medina, Pharm.D., West Side Community Health Services
DOACs for everyone? The American College of Chest Physicians (ACCP) recently updated their treatment guidelines for the prevention of stroke for patients with atrial fibrillation. Read this article to understand which patients are most likely to benefit from this update. 

From the Pharmacy Press  

A Review of Suicide Prevention Programs and Training Policies for Pharmacists
Kristine Conrow, Pharm.D., Walgreens/UMP Bethesda Clinic
Pharmacists and suicide prevention: Is there any training available?

Association Between Use of Benzodiazepines and Development of Dementia
Kyle Walburg, Pharm.D., Broadway Family Medicine
Benzodiazepine prescribing can be plagued by undesirable risks and side effect profiles; could they also be associated with the development of dementia in adults and older adult patients?

Miscellaneous News  

A Look into the Safety of Probiotic Supplements
Stephanie Walek, Pharm.D., Allina Health
Are probiotics safe for everyone? Learn about some of the potential harm these supplements pose to our patients.

Impact of the Shingrix Shortage
Jenna Gullickson, Pharm.D., CentraCare Health: St. Cloud
Ibogaine is a schedule I controlled substance in the United States but has been used for opioid withdrawal at unlicensed treatment centers in Canada and Mexico. Could ibogaine be a point of research for the treatment of opioid use disorders in the United States?

Antibiotic Overprescribing in the Outpatient Setting
Kirsten Miller, Pharm.D., FirstLight Health System
According to a new study analyzing more than half a million antibiotics prescribed in the outpatient setting, clinicians prescribed antibiotics without an infection-related diagnosis almost half of the time.

Cost-Effectiveness of a Pharmacogenetic Test to Guide Treatment for Major Depressive Disorder
Vu Ha, Pharm.D., Community University Health Care Center
Can pharmacogenomic testing improve response rate to treatment for major depressive disorder? Is this method cost effective? Read more to find out!

New Drug Updates 

XofluzaTM for the Treatment of Influenza
Anne M. Schwartz, Pharm.D., Avera Marshall
The FDA recently approved XofluzaTM for the treatment of influenza. How does this compare to TamifluTM, the current mainstay of therapy for influenza?