Curbside Consult Volume 17, Issue 4 - Fourth Quarter 2019

Research Updates 

Lung function decline in former smokers and low-intensity current smokers
Kyle Walburg, PharmD, North Memorial Camden Clinic

Is smoking less than five cigarettes per day a safe alternative to quitting? Once patients quit, is there ongoing lung function decline? New data from the NHLBI Pooled Cohorts Study offers insight.

Summary of DAPA-HF: dapagliflozin in patients with heart failure and reduced ejection fraction
McKenzie Moore, PharmD, St. Cloud VA
SGLT2 inhibitors and cardiovascular benefits – could these glucose-lowering agents be useful in patient populations without diabetes?

Does intermittent fasting really work?
Sarah Pupkes Clark, PharmD, Fairview Pharmacy Services
Calorie restriction can be difficult to sustain, pushing people to try alternative methods to lose weight, such as an intermittent fasting diet. How does intermittent fasting impact BMI, body weight, and glycemic control?

Therapeutic Thoughts

High-intensity lipid lowering in the elderly population
David Bunch, PharmD, Smiley’s Family Medicine
How should clinicians approach statin therapy in the elderly population? In the battle of prevention versus harm, which is triumphant?

Informing your patients about vaping-related lung illness
Taylor Thooft, PharmD, CentraCare - Paynesville
As more cases of vaping-related lung illness continue to be reported across the country, what information can pharmacists provide to patients to promote their safety?

2019 CAP Guidelines Update
Kylea Larsen, PharmD , Coborn’s Pharmacy/Little Falls Family Medical Center
Community-acquired pneumonia (CAP) guidelines have not been updated for more than 10 years. This article will review some of the major updates in the 2019 ATS/IDSA CAP guidelines based on the available evidence and antibiotic resistance patterns. 

From the Pharmacy Press  

Community Pharmacy Enhanced Service Network (CPESN®) now in Minnesota
Alison Kingsbury, PharmD, GuidePoint Pharmacy
Thirty-one pharmacies in Minnesota join together to create the Community Pharmacy Enhanced Services Network to change community pharmacies from dispensing-based to value-based.

Type 1 Diabetes Mellitus Treatment Options: is there more than just insulin?
Kaylin Maddy, PharmD, Park Nicollet Health Services
Treatment of type 1 diabetes mellitus is largely limited to the use of insulin. Can the use of GLP-1 agonists be expanded to patients with type 1 diabetes mellitus to target gaps in current treatment?

Treatment of Helicobacter pylori in Special Patient Populations
Andrea Richard, PharmD, Anoka Metro Regional Treatment Center / Minnesota Direct Care and Treatment
Treatment for Helicobacter pylori infection includes complex medication regimens. What are the current recommendations for treatment in patients with relative contraindications to one or more components of first-line therapies?

Miscellaneous News  

Pharmacists in California can now dispense PrEP for HIV prevention without a prescription
Vicky Wongbi, PharmD, Community University Health Care Center (CUHCC)
Pharmacists in California are at the forefront of preventing the spread of HIV infection by gaining the ability to provide Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis to patients without a prescription.

Descovy: The new era of HIV prevention
Anh Nguyen, PharmD, Walgreens / Bethesda Family Medicine Clinic
The benefits of Descovy used for HIV pre-exposure prophylaxis 

Personalizing treatments for antidepressants and antipsychotics
Anh Nguyen, PharmD, Walgreens / Bethesda Family Medicine Clinic 
The benefits of multi-gene panel testing for antidepressants and antipsychotics.