Curbside Consult Volume 16, Issue 3 - Third Quarter 2018

Research Updates 

Cross-sex Hormones and Acute Cardiovascular Events in Transgender Persons
Anjoli Punjabi, Pharm.D, MPH, FQHC Urban Network
Does use of cross-sex hormones put transgender patients at increased risk of acute cardiovascular events?

Not Just a Product of Age: Anticholinergic Medications and Falls in Middle-aged Women
Elise Durgin, Pharm.D, Goodrich Pharmacy
The risks of anticholinergic medication use in the elderly are well-known among ambulatory care pharmacists. However, findings from the Aberdeen Prospective Osteoporosis Screening Study indicate that we may need to be similarly attuned to anticholinergic burden in patients much younger than 65 years of age.

Sulfonylureas as Second Line Agents: Risk of Cardiovascular and Hypoglycemic Events
Crosby Tindal, Pharm.D., Supervalu
Sulfonylureas are frequently employed as second-line oral antihyperglycemic agents in patients who fail metformin monotherapy due to tolerability, contraindication, or inadequate therapeutic response. Long-standing concerns regarding the safety profile of sulfonylureas have complicated their place in therapy and now new evidence from real-world data adds rich considerations to this discussion. 

Therapeutic Thoughts

Omega-3 Fatty Acids: Do Cardiovascular Benefits Exist?
Ben Hierlmeier, Pharm.D., Park Nicollet
A recent meta-analysis suggests there are no cardiovascular benefits associated with omega-3 fatty acid supplement consumption. Are these results conclusive?

As-needed Budesonide-formoterol in Mild Asthma
Stephanie Keller, Pharm.D, Coborn’s Pharmacy / CHI St. Gabriel’s Health Family Medical Center
Two recent clinical trials have investigated the use of as-needed budesonide-formoterol in patients with mild asthma. What is the clinical impact of this new evidence?

Efficacy of the New Intranasal Live Attenuated Influenza Vaccine for the 2018-2019 Season
George Cullina, Pharm.D, Cashwise Clinic Pharmacy / ACMC
The intranasal influenza vaccine was officially taken off of the CDC ACIP list before the 2016-2017 flu season. Can this vaccine’s new formulation be trusted for the 2018-2019 flu season?

From the Pharmacy Press  

Impact of Pharmacist-physician Collaborative Care Model on Patient Outcomes and Health Services Utilization
Kendra Babcock, Pharm.D., CentraCare Paynesville Hospital and Clinic
Six rural hospitals in southwest Virginia integrated a pharmacist-physician collaborative care model involving hospital discharge and quarterly patient follow-ups.

Analysis of 2017 Prescription Drug Expenditure in the United States
Michelle Mages, Pharm.D., Hennepin Healthcare
In 2017, $455.9 billion were spent on prescription drugs in the United States. Learn how this compares to past years and discover what may impact expenditures for 2018.

Patient Satisfaction with Pharmacist-Administered Long-Acting Injectable Antipsychotics
Swetha Pradeep, Pharm.D, Community-University Health Care Center (CUHCC)
What role do community pharmacists play in increasing access to mental health services? This study surveyed patients receiving their long-acting injectable antipsychotic from a community pharmacist to evaluate their satisfaction with the service.

Miscellaneous News  

Fluoroquinolone Impact on Mental Health and Blood Sugars
Sara Massey, Pharm.D, Smiley’s Family Medicine Clinic
The FDA recently released a statement about new risks associated with the use of fluoroquinolones.  Before you prescribe one of these antibiotics, be sure to consider the risks and benefits for each individual patient!  

Ibogaine for Opioid Withdrawal
Michelle Tran, Pharm.D., Fairview Pharmacy Services
Ibogaine is a schedule I controlled substance in the United States but has been used for opioid withdrawal at unlicensed treatment centers in Canada and Mexico. Could ibogaine be a point of research for the treatment of opioid use disorders in the United States?

Type 2 Diabetes and Depression - Updates from the ADA Symposium
Rachel Wilhelm, Pharm.D, Westside Community Health Services
What is the link between diabetes and depression?