News and Events
Dr. Lisa Coles, MS, PhD, named to the International Leaque Against Epilepsy/American Epilepsy Society Joint Transitional Task Force
The International League Against Epilepsy/American Epilepsy Society recently invited Dr. Lisa Coles to sit on the new TASK3 working groups for three years. She will be participating in the TASK3‐WG1A which will continue the effort to create preclinical epilepsy common data elements for general pharmacology, treatment administration and tolerability studies aiming to develop new therapies for seizures and epilepsy. Congratulations, Lisa, on being recognized as a major player in the international epilepsy community!
UMN Students Present Poster as Part of ACCP Clinical Research Challenge
The University of Minnesota College of Pharmacy team, which includes CODR's Parker Johnson, presented a poster (Antibiotic Stewardship in a Small Hospital: Overcoming Barriers with Telemedicine) last week at the American College of Clinical Pharmacy (ACCP) Annual Global Conference in Seattle, part of the reward for winning first place in the ACCP Clinical Research Challenge. Each student also received a $500 cash prize and an individual plaque; the team also brought home a team trophy.
University of Minnesota College of Pharmacy's Center for Orphan Drug Research ranks top 5
CODR is featured as one of the five rare disease education programs on Rare Disease Report. https://www.raredr.com/news/five-rare-disease-educational-programs/
Congratulations to Usha Mishra
At an event on October 4, Usha Mishra, CODR Researcher, had the opportunity to meet and talk with 2014 Nobel Peace Prize recipient Kalish Satyarthi. His goal is to end exploitation of children and child labor in the world. Quite a unique opportunity!
Congratulations to Natalie Schmitz
On September 27, Natalie Schmitz, PharmD, ECP graduate student and mentee of Jim Cloyd successfully defended her PhD dissertation entitled “Orphan Drug Development: The Regulatory, Economic, and Scientific Aspects of Intravenous Baclofen.” Her seminar attracted a large audience of faculty and students, was well designed and presented. During the private exam, Natalie exhibited a good level of mastery over the wide range of topics addressed in her thesis ranging from the unmet need for IV baclofen, prevalence issues and computation, Orphan Drug Act considerations, and pk and BE principles and study designs. Her ability to competently address questions across these subjects is testimony to her hard work and ability. Natalie will assume a faculty position as an assistant professor at the University of Wisconsin School of Pharmacy on Nov 1, 2018. She intends to continue her research on treatment of spasticity. Congratulations, Natalie!
Dr. Lisa Coles and Dr. Reena Kartha are newly appointed as Research Assistant Professors within the department
The Department of Experimental and Clinical Pharmacology is pleased to announce that Dr. Lisa Coles and Dr. Reena Kartha are newly appointed as Research Assistant Professors within the department. Both have been working as researchers in the Center for Orphan Drug Research and will continue to do so in their new roles.
Lisa Coles received her PhD in Pharmaceutical Sciences from the University of Maryland in 2009, having also earned an MS in Biomedical Engineering in 2000 from the University of Minnesota. She returned to Minnesota in 2009 as a Post-Doctoral Fellow in the Center for Orphan Drug Research (CODR).
Dr. Coles' research program focuses on three therapuetic areas: epilepsy, Parkinson's Disease and diabetes, specifically the impaired awareness of hypoglycemia. Reena Kartha received her PhD in Life Sciences in 2005 from the Indian Institute of Science in Bangalore. She had previously earned an MS in Biotechnology from the Center for Plant Molecular Biology of Tamil Nadu Agricultural University in Coimbatore, India. Dr. Kartha joined the University of Minnesota in 2009 as a research associate in the Department of Pharmaceutics before moving to CODR in 2011. Her current research focuses on rare neurogenerative disorders and the identification of related novel blood and brain biomarkers.
Both Dr. Coles and Dr. Kartha have been valued colleagues for many years, and we are delighted that these new positions recognize the value of their contributions to CODR, to ECP and to the field.
Keep up to date with the events of CODR
Check out their July newsletter
Dr. Reena Kartha will present "Biomarker Discovery and Translational Pharmacology of N-acetylcysteine: Application in Gaucher disease"
July 17, 10:00 am in WDH 7-193/ ITV LSci 160
Dr. Lisa Coles will present "Applications of Pharmacometrics in Drug Development: Bidirectional Research in Animals and Humans"
July 18, 10:00 am in WDH 7-193/ ITV LSci 160
University of Minnesota College of Pharmacy Wins 2018 ACCP Clinical Research Challenge
Congratulations to CODR's Parker Johnson for his team's 2018 ACCP Clinical Research Challege win! Their proposal title was "Antibiotic Stewardship in a Small Hospital: Overcoming Barriers with Telemedicine," and their team members included Karla Marz and Victoria Smith, with Ann Philbrick as their faculty liaison.
Congratulations to Reena Kartha, MS, PhD
Congratulations to Reena Kartha on her new role as Associate Director, Clinical Pharmacology and Pharmacometrics for the Center for Orphan Drug Research.
Congratulations to Lisa Coles, MS, PhD
Congratulations to Lisa Coles on her new role as Associate Director, Clinical Pharmacology and Pharmacometrics for the Center for Orphan Drug Research.
Jillian Brooks Awarded a Summer Research Fellowship in Chemistry
Jillian Brooks, undergraduate in chemistry in the College of Science and Engineering, was recently awarded a Summer Research Fellowship in Chemistry (Heisig/Gleysteen). Jillian has been working with Dr. Lisa Coles at the Center for Orphan Drug Research on a project to measure naloxone in human plasma samples. Her research project is a component of a larger project designed to determine whether intranasal naloxone can preserve hypoglycemia counterregulation following exercise in individuals with type 1 diabetes (PI, Dr. Seaquist). The Heisig/Gleysteen Fellowship is a very competitive award and will allow her to work with us over the summer on this exciting project. Congrats Jillian!
James Cloyd Awarded the Faculty Recognition Award from the Pharmacy Alumni Socitety
James Cloyd is a Morse Alumni Distinguished Teaching Professor, the Lawrence C. Weaver Endowed Chair in Orphan Drug Development, and Director of the Center for Orphan Drug Research at the University of Minnesota College of Pharmacy and is renowned in the area of epilepsy and clinical pharmacology.
Jim has been a strong supporter of students and alumni through-out his time at the University of Minnesota. He is a former Century Mortar Club board member who was a speaker at the University of Minnesota’s Mini-College in Florida. According to his nominator, “...no one was more instrumental in my desire to further my education in pharmacy and pursue a PharmD degree than Dr. Cloyd. His skill in working with pharmacy and graduate students is unmatched. His commitment to patient care is steadfast.”
Irene Vuu Awarded a Second Year of Fellowship from American Foundation for Pharmaceutical Education
Irene Vuu has received an award that will help fund the next year of her PhD program from the American Foundation of Pharmaceutical Education (AFPE). Congratulations!
Junior Mentor of the Year: Dr. Reena Kartha
Reena Kartha, PhD, is a Research Assistant Professor with the College of Pharmacy’s Department of Experimental and Clinical Pharmacology and a Principal Scientist for the Center for Orphan Drug Research.
Her research focuses on the role of oxidative stress and inflammation in neurodegenerative conditions. Dr. Kartha generously helps interview applicants for CTSI's summer programs.
Mentees and a colleague praised Dr. Kartha for her intelligence, strength, open personality, research expertise, and for dedicating herself to her mentees’ success. Congratulations, Dr. Kartha!
James Cloyd Receives the J. Kiffin Penry Award for Excellence in Epilepsy Care
James Cloyd, PharmD, received the American Epilepsy Society (AES) 2017 J. Kiffin Penry Award for Excellence in Epilepsy Care.
Established in 1997 with an original gift from Abbott Laboratories and now supported through the J. Kiffin Penry Fund of AES, this award honors Dr. Penry's lifelong focus on and genuine concern for the patient with epilepsy. It recognizes individuals whose work has had a major impact on patient care and improved the quality of life for persons with epilepsy as well as recognizing excellence in the care of persons with epilepsy.
"The award is particularly meaningful to me as I worked closely with Dr. Penry during the early years of my career," said Cloyd. "He set a standard for excellence in patient care, education, and research that I've tried to emulate."
Cloyd received the award at the 2017 AES Annual Meeting in Washington, D.C. onDec. 4.
Kendra Radtke receives the UCSF School of Pharmacy Dohmen Life Science Scholarship.
Kendra Radtke received The Dohmen Life Science Scholarship for the 2016-2017 academic year from the University of California, San Francisco School of Pharmacy. The Dohmen Life Science Scholarship, in memory of Dr. Sally Van Doren, is awarded to a Pharmacy student and based upon demonstrated leadership, entrepreneurial spirit, a desire to serve the life sciences industry, outstanding academic achievement and financial need.
Before entering the UCSF PharmD program, Kendra earned her Bachelor of Science degree from the University of Minnesota, College of Biological Sciences. Kendra’s undergraduate research and training was completed in the Center for Orphan Drug Research under the direction of Drs. Lisa Coles and James Cloyd.
Students working with Center for Orphan Drug Research receive notable awards.
David Kraus is a senior majoring in chemistry in the UMN College of Science and Engineering. David received a Heisig/Gleysteen Chemistry Summer Research Program award. The program is designed to encourage students in chemistry to learn more about research and provide them with the opportunity to work in a lab under the direction of a faculty member. Dr. Lisa Coles assisted with the award application and will be the mentor for David’s summer project.
David Kraus and Patricia Maglalang (also a senior majoring in chemistry in the UMN College of Science and Engineering) were both chosen to receive the David A. and Merece H. Johnson Scholarship for outstanding achievement in undergraduate research as well as overall scholastic excellence. The scholarship will be awarded to these students at the beginning of the Fall 2016 term. Dr. Lisa Coles served as a research mentor to both students. Dr. James Cloyd and Dr. Ronald Siegel will be Patricia’s project mentors.
Congratulations to Bridget Curtin!
Bridget is an undergraduate student in the UMN College of Biological Sciences majoring in Biology with an expected graduation date of May 2017. Bridget has been working with the Center for Orphan Drug Research beginning in the fall of 2015.
Bridget received a financial support award for her project MicroRNAs as Potential Biomarkers for Pediatric Epilepsies under the Undergraduate Research Opportunities Program (UROP) and was selected as a 2016 Pathways to Research Program Scholar. Dr. Reena Kartha is her mentor.
James Cloyd, PharmD, Director of the Center for Orphan Drug Research, is honored at a "40 & 10" reception on March 29, 2016 McNamara Alumni Center.
Family, friends and colleagues gathered to celebrate Dr. Cloyd's career milestone and continuing good work; 40th year leading epilepsy and orphan drug research at the University of Minnesota and 10th anniversary leading the U of M Center for Orphan Drug Research.
You can congratulate Dr. Cloyd by following this link.
Zahra Karimian, PharmD - Postdoctoral Associate in the College of Pharmacy and affiliated with the Center for Orphan Drug Research - recently presented a poster at the WORLDSymposium 2016
In San Diego, CA titled "Characterizing Infusion Reactions to Intravenous Enzyme Replacement Therapy: Establishing Temporal Relationships for Effective Management Strategies" The authors are Zahra F. Karimian, PharmD; Chester B. Whitley PhD MD; and Jeanine R. Jarnes Utz, PharmD.
James Cloyd, PharmD, Director of the Center for Orphan Drug Research, presents to Robbinsdale Area Schools
Dr. Cloyd gave a talk on seizure rescue therapy titled "Use of Intranasal and Buccal Midazolam as Seizure Rescue Therapy" to the Robbinsdale Area Schools health staff. According to Amber Spaniol, RN PHN LSN, Health Services Program Director "The feedback from the nurses was great! They really enjoyed your presentation and we learned so much."
Jim Cloyd, PharmD and Reena Kartha, PhD interviewed for article in Laboratory Equipment Magazine
Jim Cloyd, PharmD and Reena Kartha, PhD were interviewed for an article in Laboratory Equipment Magazine titled “Orphan Drugs: Rare Diseases, Rare Funding”. The Center for Orphan Drug Research (CODR) was one of two major research institutions featured that are working to tackle the orphan disease problem. Read the article.
Save the Date: Rare Disease Day 2019
Save the date for our 2019 Event!
March 1, 2019
The Graduate Hotel
The goal of Rare Disease Day is to raise awareness about rare diseases and their impact on patients’ lives!