Melanie Nicol, PharmD, PhD

Associate Professor, Department of Experimental and Clinical Pharmacology (ECP)

Melanie Nicol

Contact Info

Office Phone 612-301-9511

Fax 612-626-9985

Office Address:
MTRF 4-210

Mailing Address:
Experimental and Clinical Pharmacology
2001 6th St SE
MTRF 4-210
Minneapolis, MN 55455

Lab Address:
MTRF 4-421

North Carolina Collaborative Clinical Pharmacology NIH Postdoctoral Training Program, UNC-Duke, Chapel Hill, NC

PharmD, Ohio Northern University Raabe College of Pharmacy

PhD, Pharmaceutical Sciences, UNC Eshelman School of Pharmacy, Chapel Hill, NC



HIV and Opportunistic Infections
Clinical Pharmacology
Women's Health
Drug Metabolism and Transport

Awards & Recognition

  • 2021 Society of Infectious Diseases Young Investigator of the Year 2016
  • Deborah E. Powell Center for Women's Health Research Scholar

Professional Associations

Society of Infectious Disease Pharmacists
American Society of Clinical Pharmacology and Therapeutics
American Association of Pharmaceutical Scientists
American College of Clinical Pharmacy


Research Summary/Interests

Expertise: Drug formulation, delivery and pharmacokinetics, Drug kinetics, metabolism and toxicology, Infectious diseases.

The research efforts of my lab are focused on identifying factors that influence the efficacy of antivirals (and other anti-infectives) in tissue compartments. We are working to describe the penetration of drugs used to treat HIV and related infections into tissue compartments such as the genitals, brain, and lymph tissue. There is a paucity of data on the factors that modulate drug efficacy in tissue compartments yet drug distribution to these tissues is critically important for HIV prophylaxis, suppression of viral shedding, and eradication of viral reservoirs. Our translational lab uses a variety of research approaches with projects spanning in vitro, ex vivo, and clinical studies. We have active studies in both Minnesota as well as Kampala, Uganda.



Teaching Areas

Antivirals; Pharmacotherapy of Infectious Disease


PHAR 6768: Infectious Disease


Board Certifications

American Board of Clinical Pharmacology