Vadim J. Gurvich, PhD, MBA
Research Associate Professor, Department of Medicinal Chemistry
Contact Info
Research Associate Professor, Department of Medicinal Chemistry
Associate Director, ITDD; Director, Chemical Process Development, Institute for Therapeutics Discovery and Development (ITDD)
PhD, Hebrew University of Jerusalem, 1996
MBA, University of Kansas, 2003
MS, Mendeleev University of Chemical Technology, 1987
Research
Research Summary/Interests
- Drug discovery
- Drug synthesis
- Drug development
- Synthetic organic and medicinal chemistry
Publications
1.Hussain, A. S.; Gurvich, V. J.; Morris, K. Pharmaceutical "new prior knowledge": twenty-first century assurance of therapeutic equivalence. AAPS PharmSciTech 2019, 20, 140.
2.Boyce, H.; Smith, D.; Byrn, S.; Saluja, B.; Qu, W.; Gurvich, V. J.; Hoag, S. W. In vitro assessment of nasal insufflation of comminuted drug products designed as abuse deterrent using the vertical diffusion cell. AAPS PharmSciTech 2018, 19, 1744-1757.
3.Patil, S.; Lis, L. G.; Schumacher, R. J.; Norris, B. J.; Morgan, M. L.; Cuellar, R. A.; Blazar, B. R.; Suryanarayanan, R.; Gurvich, V. J.; Georg, G. I. Phosphonooxymethyl prodrug of triptolide: synthesis, physicochemical characterization, and efficacy in human colon adenocarcinoma and ovarian cancer xenografts. J. Med. Chem. 2015, 58, 9334-9344.
4.Kirtane, A. R.; Wong, H. L.; Guru, B. R.; Lis, L. G.; Georg, G. I.; Gurvich, V. J.; Panyam, J. Reformulating tylocrebrine in epidermal growth factor receptor targeted polymeric nanoparticles improves its therapeutic index. Mol. Pharm. 2015, 12, 2912-2923.
5.Dosa, P. I.; Georg, G. I.; Gurvich, V. J.; Hawkinson, J. E.; Walters, M. A.; Wong, H. L. From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota. Comb. Chem. High Throughput Screen. 2014, 17, 231-240.