Melanie Nicol, PharmD, PhD

Nicol Research Website

• 2021 Society of Infectious Diseases Young Investigator of the Year 2016
• Deborah E. Powell Center for Women's Health Research Scholar

Society of Infectious Disease Pharmacists
American Society of Clinical Pharmacology and Therapeutics
American Association of Pharmaceutical Scientists
American College of Clinical Pharmacy

Expertise: Drug formulation, delivery and pharmacokinetics, Drug kinetics, metabolism and toxicology, Infectious diseases.

The research efforts of my lab are focused on identifying factors that influence the efficacy of antivirals (and other anti-infectives) in tissue compartments. We are working to describe the penetration of drugs used to treat HIV and related infections into tissue compartments such as the genitals, brain, and lymph tissue. There is a paucity of data on the factors that modulate drug efficacy in tissue compartments yet drug distribution to these tissues is critically important for HIV prophylaxis, suppression of viral shedding, and eradication of viral reservoirs. Our translational lab uses a variety of research approaches with projects spanning in vitro, ex vivo, and clinical studies. We have active studies in both Minnesota as well as Kampala, Uganda.

Full publication list at:

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Pubmed