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Yusuf J. Abul-Hajj
Professor
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Aromatase, estrogen synthetase, steroid chemistry, steroid biochemistry, carcinogenesis, breast cancer, estrogen carcinogenesis
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Elizabeth A. Amin
Assistant Professor |
Computer-aided drug discovery, lead optimization, 3D-QSAR/QSPR, ADME/Tox, zinc metalloenzymes, quantum mechanics, bio- and cheminformatics, modeling transition metals in macromolecules and nanoparticles
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Mark D. Distefano
Associate Professor |
Bioorganic chemistry, enzymology, organic synthesis, protein prenylataion, sesquiterpene biosynthesis, rubber biosynthesis, protein labeling and immobilization, photoaffinity labeling, caged substrates.
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Robert A. Fecik
Assistant Professor
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Novel antibiotics, chemotherapeutic agents, total synthesis, combinatorial chemistry, combinatorial biosynthesis, pikromycin biosynthesis
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David M. Ferguson
Associate Professor
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Quantum mechanics, molecular mechanics/dynamics, computer graphics techniques, molecular interactions, investigation of inter- and intramolecular interactions to gain insight for drug design and protein engineering
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Gunda I. Georg
Professor and Department Head 2007 |
Design, synthesis, and evaluation of synthetic and natural product-derived medicinal agents; drug discovery by HTS; new synthetic methods; combinatorial chemistry. Therapeutic areas: cancer, male contraception, Alzheimer's disease.
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William B. Gleason
Associate Professor
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Computational biology, structure-based computer modeling, sulfated carbohydrate polymers, proteomics applications
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Patrick E. Hanna
Professor
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Bioactivation reactions catalyzed by N-acetyltransferases, biotransformation and fate of carcinogenic aryalamines, characterization of the catalytic mechanism and active site topologies of arylamine N-acetyltransferases
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Stephen S. Hecht
Professor and Wallin Chair in Cancer Prevention
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Mechanism by which carcinogens are metabolically activated and detoxified in humans, cancer prevention, nitosamines, aldehydes, and polycyclic aromatic hydrocarbons
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Thomas Hoye
Professor
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Organic synthesis, natural products, analogs and prodrugs, symmetry concepts, organometallic chemistry,NMR spectroscopy
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Rodney L. Johnson
Professor and Intrim Head
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Design and synthesis of novel analogues of amino acids and peptides, peptidomimetcs
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Ramaiah Muthyala
Research Associate Professor
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Novel antibiotics, fatty acid synthase inhibitors, secretase inhibitors, natural products as drug leads, organic synthesis, combinatorial chemistry, molecular modeling.
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Krzysztof Pankiewicz
Associate Professor
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Chemistry of nucleosides, nucleotides, and nucleic acids components, modified cofactors as enzymes inhibitors, novel antibiotics, and synthesis of compounds with potential antiviral activity.
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Lisa Peterson
Associate Professor
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Genotoxic and nongenotoxic mechanisms by which chemicals initiate cancer
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Philip S. Portoghese
Distinguished Professor
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G protein-coupled receptors; molecular recognition; opioid receptors; bivalent ligands; affinity labels
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Rory P. Remmel
Professor
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Drug metabolism and disposition, evaluation of antiviral drug combinations, metabolic interactions of antiepileptic drugs in the elderly
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W. Thomas Shier
Professor
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Development of novel non-viral vector transfection agents for use in human gene therapy, strategies for eliminating carcinogenic and estrogenic mycotoxins from the human food supply, exploration of the drug potential of betulins and other natural products
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Shana Sturla
Assistant Professor
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Chemoprevention, Carcinogenesis, DNA Adducts, Cancer Biomarkers, Organic Synthesis
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Natalia Tretyakova
Associate Professor
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Structural basis for promutagenic and anticancer activity of DNA-modifying agents, DNA damage by tobacco carcinogens and lung cancer, DNA-DNA and DNA-protein cross-linking agents as carcinogens and drugs, DNA oxidation by endogenous reactive oxygen species
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Robert Vince
Professor
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Anti-HIV drugs, anti-herpes agents
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Carston R. Wagner
Professor
Director of Graduate Studies
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Chemical Biology, design and development of targeted drug delivery approaches, design and study of chemical inducers of protein oligomerization, mechanistic and structural studies of biocatalysis and protein translation
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Chengguo Xing
Assistant Professor
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Developing small molecules targeting specific Bcl-2 proteins as potential therapeutic agents and biological tools, elucidating chemical and biological processes in apoptotic regulation by Bcl-2 proteins, and characterizing various apoptotic processes induced by different stimuli
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