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Medicinal Chemistry > Graduate Program > Recent Degrees Conferred

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Recent Degrees Conferred


Doctoral Theses

Nam

Title

Advisor

Date

Ding Lu The Design, Synthesis and Biological Evaluation of Pseudosymmetric HIV-I Protease Inhibitors Featuring Sulfoximine Functionality as a Potential Transition State Mimic Dr. Vince 2007
Swati S. More

Design, Synthesis and Biological Evaluation of Glutathione Peptidomimetics as Components of Targeted Prodrugs and Glyoxalase I Inhibitors

Dr. Vince 2007
Tsui-Fen Chou

Histidine Triad Nucleotide Binding Proteins (Hints): Nucleoside Phosphoramidases and Potential Regulators of Aminoacyl – tRNA Synthetases Dr. Wagner

Dr. Wagner  2006
Brian Kane

Molecular Recognition of G – Protein Coupled Receptor Ligands: Insights into Salvinorin A and Xanomeline

Dr. Ferguson 2006
Upendra Argikar

Effects of Age, Induction, Regulation and Polymorphisms on the Metabolism of Antiepileptic Drugs

Dr. Remmel 2006
Yabin Lao

Analysis by HPLC – ESI – MS/MS of Pyridyloxobutyl DNA Adducts in F344 Rats Treated with Tobacco – Specific Nitrosamines

Dr. Hecht 2006
David S. Daniels

Bivalent Opioid Ligands as Probes for the Investigation of Opioid Receptor Dimerization. Development of Novel Analgesics without Tolerance or Physical Dependence

Dr. Portoghese 2006
John Goodell

Synthesis and Evaluation of Heterocyclic Antiviral Agents

Dr. Ferguson 2006
Bhooma Raghavan

Synthesis of 5.6.5 Spiro Bicyclic Lactams and Photoaffinity Labeling Ligands for PLG Binding Site and Stereoseletive Synthesis of a – Substituted y – Lactams

Dr. Johnson

2006
Ashish P. Vartak

Design and Synthesis of Type – VI – ß – Turn Mimics of L – Prolyl – Xaa – L – Prolinamide

Dr. Johnson 2006
Xingnan Li

Synthesis and Biological Evaluations of Conformationally Restrained a, y-Diketo Acid Analogs and Purine-Containing Mg2+ Chelating Ligands as Inhibitors for HIV Integrase

 Dr. Vince 2005
Abigail Fisher

Photoaffinity Labeling and Conformationally Constrained Analogs of the Dopamine Receptor Modulator L-Prolyl-L-Leucyl-Glycinamide

Dr. Johnson  2005
Jonathan Carlson

Towards Therapeutic Nanoassemblies: Chemically Induced Protein Oligomerization 2005

Dr. Wagner 2005
Ye Tang

Synthesis and Biological Evaluation of Unsaturated Carbo-Acyclic Nucleosides

Dr. Vince

2005

Haiqing Wang

Studies on Arylamine N-Acetyltransferases

Dr. Hanna

2004

Eric Jorvig

Synthesis and Evaluation of Acidone Antiviral Agents

Dr. Ferguson

2004

Zhijun Guo

Studies on Hamster Recombinant Arylamine N-Acetyltransferases

Part I: Covalent Modification and Inactivation of rNAT1 by Bromoacetamido Derivatives of Aniline and 2-Aminofluorene

Part II: Mass Spectrometric Investigation of the Inactivation of rNAT1 by N-Hydroxy-2-Acetylaminofluorene

Dr. Hanna

2004

Sathit Niratisai

Synthesis of 14beta-Amino Isosteric Analogs of Naltrindole and Norbinaltorphimine: Role of 14beta-Amino Group and its Acyl Substituents on Delta- and Kappa-Selective Opioid Receptor Antagonism

Dr. Portoghese

2003

Mahadevan Seetharaman

Studies on DNA Recognition by Structure-Selective Nucleases Using Molecular Dynamics Simulations and Molecular Docking

Dr. Ferguson

2003

Sarika Prabhu Design and Synthesis of Conformationally Constrained Analogs of L-AP4 and MAP4 as Metabotropic Glutamate Receptor Ligands Dr. Johnson 2002

Rashmi Gupta Bhushan

Synthesis and Biological Evaluation of Carbocyclic and other Non-Glycosidic Nucleosides

Dr. Vince

2001

Masters Theses

Name

Title

Advisor

Date

John Giraldes

John Giraldes (MS) “Substrate Specificity and Affinity Labeling Studies of Polyketide Synthase Thioesterases

Dr. Fecik 2006
Jaeson Steel Progress towards the Synthesis of the Tubulysins Dr. Shier 2008
Priyanka A Rao

Analysis of Phenathrene Metabolite by Liquid Chromatography – Tandem Mass Spectrometry

Dr. Hecht 2005

Natarajan Kalyanaraman

Inhibition of Naltrexone metabolism by NSAIDs leading to metabolic switching and reactive metabolite formation

Dr. Remmel

2004

Rebecca Ziegel

Effects of Sequence Context and Cytosine Methylation on DNA Reactions with Tobacco Carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Dr. Tretyakova

2003

 

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