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Medicinal Chemistry > News and Events > Graduate Student News

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Graduate Student News


Congratulations!

Dr. Brian Kane is now a post-doctoral fellow at Prof. Dirk Trauner's lab in the Dept. Chemistry at the University of California, Berkeley. Good Luck!

Dr. Goodell received his B.S. in Chemistry from the University of Wisconsin-River Falls.  He received his Ph.D. in Medicinal Chemistry in April 2006 here at the University of Minnesota under the supervision of Dr. David Ferguson. The title of his thesis was "Synthesis and Evaluation of Heterocyclic Antiviral Agents".  John joined the Center for Chemical Methodology and Library Development at Boston University (CMLD-BU) in Boston Massachusetts as a postdoctoral scientist in August 2006 and is currently working on a project developing chemical reactions using an automated microfluidics platform. 

Awards and Presentations

Congratulations to Tsui-fen Chou for being selected for a travel award by the Division of Biological Chemistry to present her research at the National ACS meeting at San Francisco in Sept.  This is a highly competitive national award that recognizes outstanding graduate student research in the field of biological chemistry.

Melissa Goggin gave a poster presentation at the NIH Chemical Biology Training Grant Student Symposium on June 6, 2006 titled "Development of a Quantitative Capillary HPLC-MS/MS Method of bis-N7G-butanediol DNA Cross-links of Diepoxybutane."

Rebecca Guza, Mathur Rajesh, Qingming Fang, Anthony E. Pegg and Natalia Tretyakova presented their poster “O6-Alkylguanine DNA Alkyltransferase Mediated Repair of Carcinogen Induced O6-Alkyl-deoxyguanosine Lesions,” at the NIH Chemical Biology Training Grant Student Symposium as well.

Congratulations to Tsui-fen Chou for being selected for a travel award by the Division of Biological Chemistry to present her research at the National ACS meeting at San Francisco in Sept.  This is a highly competitive national award that recognizes outstanding graduate student research in the field of biological chemistry.

Tsui-fen Chou received an ASBMB Travel Award to attend the Experimental Biology 2006 Meeting, San Francisco, April 1-5, 2006.  Poster presentation: Chou, T.-F., and Wagner, C. R. “Substrate Specificity and Radioactive Labeling Studies Establish that the Histidine Triad Nucleotide Binding Proteins (Hints) are Nucleoside Phosphoramidases and Protein Nucleotidylases.”

Publications

More SS, (More, Swati S.), Vince R (Vince, Robert) "A metabolically stable tight-binding transition-state inhibitor of glyoxalase-I." Biorganic & Medicinal Chemistry Letters. 2006 Dec16(23):6039-6042

Goodell JR, Puig-Basagoiti F, Forshey BM, Shi PY, Ferguson DM.  “Identification of compounds with anti-West Nile Virus activity.” J Med Chem. 2006 Mar 23;49(6):2127-37.

Goodell JR, Svensson B, Ferguson DM.  “Spectrophotometric determination and computational evaluation of the rates of hydrolysis of 9-amino-substituted acridines.” J Chem Inf Model. 2006 Mar-Apr;46(2):876-83.

Goodell JR, Madhok AA, Hiasa H, Ferguson DM.  “Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity.” Bioorg Med Chem. 2006 May 17.

Kane BE, Svensson B, Ferguson DM. “Molecular recognition of opioid receptor ligands.” AAPS J. 2006 Mar 10;8(1):E126-37.

Kane B E., Nieto M J., McCurdy C R., Ferguson DM. “A unique binding epitope for salvinorin A, a non-nitrogenous kappa opioid receptor agonist.” FEBS J. 2006 May;273(9):1966-74.

Jonathan T. C. Carlson ('06) and Tsui-fen Chou recently published "chemicallly controlled self-assembly of protein nanorings", J. Amer. Chem. Soc. 2006. 128, 7630-7638.

Rachel Loeber is the first author on May's cover article in Chemical Research in Toxicology.  Rachel is a third year student supported by the University of Minnesota Chemical Biology Training Grant.
 
Loeber R, Rajesh M, Fang Q, Pegg AE, Tretyakova N.  "Cross-linking of the human DNA repair protein O6-alkylguanine DNA alkylatransferase to DNA in the presence of 1,2,3,4-diepoxybutane."  Chem. Res. Toxicol. 2006. 19(5), 645-654.
 
http://pubs.acs.org/journals/crtoec/index.html

 

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