William Oetting

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William Oetting, Ph.D.

Academic Title

Experimental and Clinical Pharmacology

Contact Info




Office Address

14-255 Moos Tower

Mailing Address

University of Minnesota
College of Pharmacy
Department of Experimental and Clinical Pharmacology
7-115 Weaver-Densford Hall
308 Harvard St. SE
Minneapolis, MN 55455

Bio Statement

Link to Pharmacogenomics U of M Alliance - Institute of Personalized Medicine (PUMA - IPM)

Research Interests

  • Genetic analysis of genes and gene polymorphisms associated with solid organ transplant outcome
  • Genetics of behavioral disorders
  • Proteomic and metabolomic analysis of kidney disease


Jackola DR, Basu S, Liebeler CL, Willaert R, Luah SS, Oetting W, King RA, Blumenthal MN. 2006. Inheritance of CD14 promoter polymorphisms in atopic families: Implications for modulated allergen-specific IgE and IgG1 responses. International Archives of Allergy & Immunology 139:217-24. [PMID: 16446545]

Oetting WS, Rogers TB, Krick TP, Matas AJ, Ibrahim H. 2006. β2-microglobulin is a urine biomarker associated with acute kidney allograft rejection. American Journal of Kidney Disease 47:898-904. [PMID: 16632030]

Argikar UA, Cloyd JC, Birnbaum AK, Leppik IE, Conday J, Kshirsagar S, Oetting WS, Klein EC, Remmel RP, 2006, .Parodoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients. Epilepsy Research 71:54-63. [PMID: 16815679]

Wahlstrom D, White T, Hooper CJ, Vrshek-Schallhorn S, Oetting WS, Luciana M. 2007. Variations in the catechol O-methyltransferase polymerase and prefrontally-guided behaviors in adolescents. Biological Psychiatry. 61:626-632. [PMID: 17014828]

Chan PA, Duraisamy S, Newell JA, Miller PJ, McBride C, Bond JP, Raevaara T, Ollila S, Nyström M, Grimm A, Christodoulou J, Oetting WS, Greenblatt MS. 2007. Interpreting missense variants: validation of comparative sequence analyses in human disease genes CDKN2A, MLH1, MSH2, MECP2, and Tyrosinase. Human Mutation 28:683-693. [PMID: 17370310]

Reilly C, Miller MB, Liu Y, Oetting WS, King R, Blumenthal M. 2007. Linkage analysis of a cluster-based quantitative phenotype constructed from pulmonary function test data in 27 multigenerational families with multiple family members. Human Heredity 64:136-145. [PMID: 17476113]

Irons, DE, McGue M, Iacono WG, Oetting WS. 2007. Mendelian randomization: A novel test of the gateway hypothesis. Development and Psychopathology 19:1181-1195. [PMID: 17931442]

Kumar, V, Brundage RC, Oetting WS, Leppik IE, Tracy TS. 2008. Differential Genotype Dependent Inhibition of CYP2C9 in Humans. Drug Metabolism and Disposition 36:1242-8. [PMID: 18378563]

Oetting WS. 2008. Large scale sequencing – New challenges emerge. The 2007 Human Genome Variation Society Scientific Meeting. Human Mutation 29:765-768 [PMID: 18348287]

Johnson LA, Oetting WS, Basu S, Prausa S, Matas A, Jacobson P. 2008. Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors. European Journal of Clinical Pharmacology 64:1047-1056. [PMID: 18568343]

Akkina S, Zhang Y, Nelsestuen G, Oetting WS, Ibrahim HN. 2009. Temporal stability of the urinary proteome after kidney transplant: more sensitive than protein composition? Journal of Proteome Research 8:94-103. [PMID: 19012427]

Oetting WS, Pietsch, J, Brott, MJ, Savage S, Fryer JP, Summers CG, King, RA. 2009. The R402Q tyrosinase variant does not cause autosomal recessive ocular albinism. American Journal of Medical Genetics 149A:466-469. [PMID: 19208379]

Zhang Y, Oetting WS, Harvey SB, Stone MD, Monkkonen T, Matas AJ, Nelsestuen GL. 2009 Urinary protein profiles: diagnosis and prognosis of kidney transplant outcomes. Transplantation 87:1807-1813. [PMID: 19543057]

Oetting WS. 2009. Clinical Genetics & Human Genome Variation. The 2008 Human Genome Variation Society Scientific Meeting. Human Mutation 30:852-856. [PMID: 19260058]

He H, Oetting WS, Brott MJ and Basu S. 2009. Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene interaction in a case-control study. BMC Medical Genetics 10:127. [PMID: 19961594]

He H, Oetting WS, Brott MJ and Basu S. 2010. Pair-wise multifactor dimensionality reduction method to detect gene-gene interactions in a case control study. Human Heredity 69:60-70. [PMID: 19797910]

Oetting WS. 2010. Impact of next generation sequencing: The 2009 Human Genome Variation Society scientific meeting. Human Mutation 31:500-503 [PMID: 20127974]


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  • Last modified on December 18, 2013