Haim Einat Assistant Professor Department of Pharmacy Practice and Pharmaceutical Sciences Office: 123 Life Science, Duluth Telephone Number: 218-726-6029 E-mail Address: heinat@umn.edu

Education:

Post-Doc, Fellow, behavioral specialist–NIMH
Ph.D., Ben Gurion University of the Negev, Israel
MS Biomed. and Behav. Sci., McMaster University, Canada
MS Zoology, Tel-Aviv University, Israel
BS Biology, Tel-Aviv University, Israel
B.Med.SC., Hebrew University of Jerusalem, Israel

Research Interests:

My research uses animal models to explore the biological basis of affective and anxiety disorders and develop better treatments for these devastating diseases.  I work on the development and validation of better animal models for these diseases and utilize both established and novel models to explore behaviorally specific intracellular molecules and pathways that are implicated in affective disorders and its treatments. I am currently teaching CNS pharmacology and advanced psychopharmacology course to pharmacy students.

Biosketch:

http://www.d.umn.edu/ibs/Faculty/Einat2.htm

Select Publications:

Reviews

Einat H, Belmaker RH, Manji HK. New Approaches to modeling bipolar disorder - from face to construct validity. Psychopharmacology Bulletin 2003; 37(1):47-63.

Einat H, Kofman O, Belmaker RH. Animal models of bipolar disorder: from a single episode to progressive cycling models. In: M Myslobodsky & I Weiner, editors. Contemporary issues in Modeling Psychopathology. Kluwer Academic Publishers, London; 2000. pp. 165-179.

Peer Reviewed Research Papers (* equal contribution)

Einat H, Yuan PX, Manji KH. Anxiety-like behaviors and reduced mitochondrial Bcl-2 levels in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders. Behavioral Brain Research 2005: in press.

*Gould TD, *Einat H, Bhat R, Manji KH. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. Journal of Neuropsychopharmacology 2004;7:1-4.

Einat H, Yuan PX, Gould TD, Li J, Du J, Manji HK, Chen G. The role of the extracellular signal-regulated kinase signaling pathway in mood-modulation. Journal of Neuroscience 2003;23 (19) 7311-7316.

Einat H, Clenet F, Shaldubina A, Belmaker RH, Bourin M. The antidepressant activity of inositol in the forced swim test involves 5-HT2 receptors. Behavioral Brain Research 2001;118(1) 77-83.

Affiliations:

Senior member, Pharmacology Graduate Program, University of Minnesota
Member, Integrated Biosciences Graduate Program, University of Minnesota Duluth