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If you would like additional information or have questions about the Chemical Biology Initiative, contact:

Dr. Carston R. Wagner
Phone: 612-625-2614
Email: wagne003@umn.edu



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Chemical Biology Workshop

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Chemical Biology Workshop Program


Frontiers of Drug Discovery: Chemical Library Development and Screening
Coffman Memorial Union Theater (1st Floor)

7:30 a.m.

Registration

8:15 a.m.

Welcome

Carston R. Wagner, Ph.D.
University of Minnesota

8:30 a.m.

Library Screening

8:30 a.m. Anton Simeonov, Ph.D.
National Institutes of Health
“Quantitative High-Throughput Screening at the NIH Chemical Genomics Center”
9:15 a.m. Gunda Georg, Ph.D.
University of Kansas
"Academic Experiences with Chemical Libraries as Research Tools and for Drug Discovery"
9:45 a.m. Break
10:05 a.m. Bryan Roth, M.D., Ph.D.
Case Western Reserve University
"Mining the Receptorome with Small Molecules:  A Powerful Approach for Drug Discovery"
10:50 a.m. Thomas Hoye, Ph.D.
University of Minnesota
"The Sea Lamprey Migratory Pheromone Story: A Tale of Two Disciplines"

11:20 a.m.

Roundtable Discussion

All Morning Speakers

11:40 a.m.

Lunch: Provided for all Registrants

12:40 p.m.

Chemical Library Development and Natural Products

12:40 p.m. Derek Tan, Ph.D.
Memorial Sloan-Kettering Cancer Center
"Natural Product-based Strategies in Diversity-Oriented Synthesis"
1:25 p.m. Robert Fecik, Ph.D.
University of Minnesota
"Structure-based Catalyst Design for Combinatorial Biosynthesis"
1:55 p.m.

In Silico Library Methods

1:55 p.m. Matthew Jacobson, Ph.D.
University of California, San Francisco
"In Silico Prediction of Ligand Binding and Membrane Permeability Moving Beyond Empiricism"
2:40 p.m. Break
3:00 p.m. George Karypis, Ph.D.
University of Minnesota
"Structure-Based Virtual Screening and Retrieval Algorithms Drug Discovery"

3:30 p.m.

Small Molecules as Biological Tools

3:30 p.m. Junying Yuan, Ph.D.
Harvard University
"Dissecting Cell Death Signaling Using Small Molecules"
4:15 p.m. Scott Selleck, M.D., Ph.D.
University of Minnesota
"Modulating the Function of Heparan Sulfate with Small Molecule Affectors of Biosynthesis: From Chemical Libraries to Zebrafish Embyros"

4:45 p.m.

Roundtable Discussion

Afternoon Speakers

5:05 p.m.

Closing Remarks

 

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