Chemical Biology Workshop Program

Dr. Carston R. Wagner
Phone:
612-625-2614
Email:
wagne003@umn.edu

Frontiers of Drug Discovery: Chemical Library Development and Screening
Coffman Memorial Union Theater (1st Floor)

7:30 a.m.

Registration

8:15 a.m.

Welcome

Carston R. Wagner, Ph.D.
University of Minnesota

8:30 a.m.

Library Screening

8:30 a.m.	Anton Simeonov, Ph.D. National Institutes of Health “Quantitative High-Throughput Screening at the NIH Chemical Genomics Center”
9:15 a.m.	Gunda Georg, Ph.D. University of Kansas "Academic Experiences with Chemical Libraries as Research Tools and for Drug Discovery"
9:45 a.m.	Break
10:05 a.m.	Bryan Roth, M.D., Ph.D. Case Western Reserve University "Mining the Receptorome with Small Molecules: A Powerful Approach for Drug Discovery"
10:50 a.m.	Thomas Hoye, Ph.D. University of Minnesota "The Sea Lamprey Migratory Pheromone Story: A Tale of Two Disciplines"

11:20 a.m.

Roundtable Discussion

All Morning Speakers

11:40 a.m.

Lunch: Provided for all Registrants

12:40 p.m.

Chemical Library Development and Natural Products

12:40 p.m.	Derek Tan, Ph.D. Memorial Sloan-Kettering Cancer Center "Natural Product-based Strategies in Diversity-Oriented Synthesis"
1:25 p.m.	Robert Fecik, Ph.D. University of Minnesota "Structure-based Catalyst Design for Combinatorial Biosynthesis"

1:55 p.m.

In Silico Library Methods

1:55 p.m.	Matthew Jacobson, Ph.D. University of California, San Francisco "In Silico Prediction of Ligand Binding and Membrane Permeability Moving Beyond Empiricism"
2:40 p.m.	Break
3:00 p.m.	George Karypis, Ph.D. University of Minnesota "Structure-Based Virtual Screening and Retrieval Algorithms Drug Discovery"

3:30 p.m.

Small Molecules as Biological Tools

3:30 p.m.	Junying Yuan, Ph.D. Harvard University "Dissecting Cell Death Signaling Using Small Molecules"
4:15 p.m.	Scott Selleck, M.D., Ph.D. University of Minnesota "Modulating the Function of Heparan Sulfate with Small Molecule Affectors of Biosynthesis: From Chemical Libraries to Zebrafish Embyros"

4:45 p.m.

Roundtable Discussion

Afternoon Speakers

5:05 p.m.

Closing Remarks